Evidence map›Paper›PMID 34733837›Full record

ArticleFrontiers in cell and developmental biology2021

Cardiomyocyte-Specific RIP2 Overexpression Exacerbated Pathologic Remodeling and Contributed to Spontaneous Cardiac Hypertrophy.

Jing-Jing Yang, Nan Zhang, Zi-Ying Zhou, Jian Ni, Hong Feng, Wen-Jing Li, Shan-Qi Mou, Hai-Ming Wu, Wei Deng, Hai-Han Liao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Cryptotanshinone Attenuated Pathological Cardiac RemodelingOxidative medicine and cellular longevity · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jing-Jing YangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Nan ZhangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Zi-Ying ZhouDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Jian NiDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Hong FengDepartment of Geriatrics, Renmin Hospital of Wuhan University, Wuhan, China.
Wen-Jing LiDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Shan-Qi MouDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Hai-Ming WuHubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Wei DengDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Hai-Han LiaoDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Qi-Zhu TangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Renmin Hospital of Wuhan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the role and mechanisms of Receptor interacting protein kinase 2 (RIP2) in pressure overload-induced cardiac remodeling. Human failing or healthy donor hearts were collected for detecting RIP2 expression. RIP2 cardiomyocyte-specific overexpression, RIP2 global knockout, or wild-type mice were subjected to sham or aortic banding (AB) surgery to establish pressure overload-induced cardiac remodeling

Indexed as

cardiac remodelingMAPKRIP2spontaneous cardiac remodelingTAK1

Identifiers

PMID34733837
PMCPMC8559979
OpenAlexW3206834916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.