Evidence map›Paper›PMID 34733821›Full record

ReviewFrontiers in chemistry2021

Recent Advances in Second Near-Infrared Region (NIR-II) Fluorophores and Biomedical Applications.

Yingying Chen, Liru Xue, Qingqing Zhu, Yanzhi Feng, Mingfu Wu

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. High-throughput SWCNT NIR-II screening enables cell andbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingying ChenDepartment of Gynecology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Liru XueDepartment of Gynecology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Qingqing ZhuDepartment of Gynecology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Yanzhi FengDepartment of Gynecology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Mingfu WuDepartment of Gynecology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence imaging technique, characterized by high sensitivity, non-invasiveness and no radiation hazard, has been widely applicated in the biomedical field. However, the depth of tissue penetration is limited in the traditional (400-700 nm) and NIR-I (the first near-infrared region, 700-900 nm) imaging, which urges researchers to explore novel bioimaging modalities with high imaging performance. Prominent progress in the second near-infrared region (NIR-II, 1000-1700 nm) has greatly promoted the development of biomedical imaging. The NIR-II fluorescence imaging significantly overcomes the strong tissue absorption, auto-fluorescence as well as photon scattering, and has deep tissue penetration, micron-level spatial resolution, and high signal-to-background ratio. NIR-II bioimaging has been regarded as the most promising

Indexed as

biological imagingbiomedical applicationsfluorescence imagingfluorophoresNIR-II

Identifiers

PMID34733821
PMCPMC8558517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.