Evidence map›Paper›PMID 34733796›Full record

ArticleFrontiers in cellular and infection microbiology2021

Lateral Flow Immunoassay for the Detection of Panton-Valentine Leukocidin in

Abiola Senok, Stefan Monecke, Rania Nassar, Handan Celiloglu, Sreeraj Thyagarajan, Elke Müller, Ralf Ehricht

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Mechanisms of fusidic acid resistance.Biochemical Society transactions · 2025
    Review
  3. Article
  4. Clonal Complexes Distribution ofAntibiotics (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Correlation Analysis ofInternational journal of clinical practice · 2023
    Article
  7. Characterisation of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023
    Article
  8. Sequence Analysis of NovelInternational journal of molecular sciences · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Abiola SenokCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Stefan MoneckeDepartment of Optical Molecular Diagnostics and System Technology, Leibniz Institute of Photonic Technology (IPHT), Jena, Germany.
Rania NassarCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Handan CelilogluCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Sreeraj ThyagarajanDepartment of Pathology & Laboratory Medicine, Mediclinic City Hospital, Dubai, United Arab Emirates.
Elke MüllerDepartment of Optical Molecular Diagnostics and System Technology, Leibniz Institute of Photonic Technology (IPHT), Jena, Germany.
Ralf EhrichtDepartment of Optical Molecular Diagnostics and System Technology, Leibniz Institute of Photonic Technology (IPHT), Jena, Germany.
Mohammed Bin Rashid University of Medicine and Health Sciences · AEInfectoGnostics Research Campus Jena · DELeibniz Institute of Photonic Technology · DEMediclinic City Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Panton Valentine leukocidin (PVL) is a virulence factor which is associated with methicillin sensitive and resistant Methods: The study was carried out from January-August 2020 in Dubai, United Arab Emirates. Results: One-hundred thirty-five patients with a clinical diagnosis of SSTIs were recruited. Sixty-six patients received antibiotics, mostly beta lactams (n=36) and topical fusidic acid (n=15). One-hundred twenty-nine isolates (MRSA: n=43; MSSA: n=86) were tested by LFI and DNA microarrays. All 76 (58.9%) isolates which were unambiguously negative for the PVL in LFI were negative for Conclusion: LFI shows excellent diagnostic accuracy indices for rapid identification of PVL in MSSA/MRSA in a setting with high prevalence of

Indexed as

Methicillin-Resistant Staphylococcus aureusSoft Tissue InfectionsStaphylococcal InfectionsAnti-Bacterial AgentsBacterial ToxinsExotoxinsHumansImmunoassayLeukocidinsStaphylococcus aureusUnited Arab EmiratesAnti-Bacterial AgentsBacterial ToxinsExotoxinsLeukocidinsPanton-Valentine leukocidinDNA microarraylateral flow immunoassayPanton Valentine leucocidinskin and soft tissue infectionStaphylococcus aureus

Identifiers

PMID34733796
PMCPMC8558463
OpenAlexW3205957127

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.