Evidence map›Paper›PMID 34733723›Full record

ArticleGland surgery2021

Systematic review and meta-analysis of ultrasonic elastography in the diagnosis of benign and malignant thyroid nodules.

Ying Zhou, Huali Chen, Jialin Qiang, Dandan Wang

Open access · diamondAbstract read
In one paragraph

Article in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ying ZhouUltrasonography Department, Zhejiang Quhua Hospital, Quzhou, China.
Huali ChenUltrasonography Department, Zhejiang Quhua Hospital, Quzhou, China.
Jialin QiangUltrasonography Department, Zhejiang Quhua Hospital, Quzhou, China.
Dandan WangUltrasonography Department, The Second Affiliated Hospital of Zhejiang Chinese Medicine University, Hangzhou, China.
Guhua Hospital · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, ultrasound elastography (USE) has been the main diagnostic technique for benign and malignant thyroid nodules. However, it cannot display the blood flow signals of nodules with smaller diameters clearly, which decreases its diagnostic accuracy.

methodsChinese and English databases were searched using "ultrasonic elastography", "benign and malignant thyroid nodules", and "diagnose" as the search terms. RevMan 5.3 software was used for meta-analysis.

resultsA total of 11 randomized controlled trials (RCTs) were included. Eight articles analyzed clinical symptoms, and the heterogeneity test results were Chi

conclusionsThis meta-analysis confirmed that USE shows high sensitivity and specificity in diagnosing benign and malignant thyroid nodules, which could reduce the false negative rate (FNR) and false positive rate (FPR), showing high clinical diagnostic value.

Indexed as

benign and malignantthyroid nodulesUltrasound elastography (USE)

Identifiers

PMID34733723
PMCPMC8514303
OpenAlexW3200864785

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.