Evidence map›Paper›PMID 34733607›Full record

ArticleIntegrative medicine research2021

Effect of qigong exercise and acupressure rehabilitation program on pulmonary function and respiratory symptoms in patients hospitalized with severe COVID-19: a randomized controlled trial.

Shu-Ting Liu, Chao Zhan, Yun-Jing Ma, Chao-Yang Guo, Wei Chen, Xiao-Ming Fang, Lei Fang

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Integrative medicine research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05504460 naunknown statusnot on this mapstarted 2022, after this paper: background citation

A Randomized, Controlled Clinical Trial to Evaluate the Effectiveness and Safety of Hydrogen-Oxygen Generator With Nebulizer for Rehabilitation Treatment of Dysfunctions in Discharged Patients Who Are Previously Hospitalized Due to COVID-19

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2022 to 2024Enrolled216ConditionsCOVID-19, AMS-H-03, Hydrogen-oxygen GasArmsHydrogen-Oxygen Generator with Nebulizer, AMS-H-03, basic treatment
NCT05692258 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia

TypeinterventionalSponsorThe First Affiliated Hospital of Hunan University of Traditional Chinese MedicineRan2023 to 2023Enrolled146ConditionsAcupuncture, Covid-19 Omicron, Pulmonary FunctionArmsAcupuncture
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  2. Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation.European journal of physical and rehabilitation medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shu-Ting LiuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Chao ZhanHuangshi Hospital of Traditional Chinese Medicine, Hubei, China.
Yun-Jing MaDepartment of Rehabilitation, Shanghai East Hospital, Shanghai, China.
Chao-Yang GuoShanghai University of Traditional Chinese Medicine, Shanghai, China.
Wei ChenHuangshi Hospital of Traditional Chinese Medicine, Hubei, China.
Xiao-Ming FangHuangshi Hospital of Traditional Chinese Medicine, Hubei, China.
Lei FangShanghai University of Traditional Chinese Medicine, Shanghai, China.
Huangshi Central Hospital · CNShanghai University of Traditional Chinese Medicine · CNShanghai East Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are several effective complementary and integrative therapies for patients with severe COVID-19. The trial aims to evaluate the efficacy and advantages of the qigong exercise and acupressure rehabilitation program (QARP) for treating patients with severe COVID-19.

methodsA total of 128 patients with COVID-19 aged 20 to 80 years were recruited and randomly allocated in a 1:1 ratio to receive QARP plus standard therapies or standard therapies alone. QARP consisted of acupressure therapy and qigong exercise (

resultsIn total, 128 patients completed the clinical trial. The QARP group and standard therapies group showed significant improvements in vital signs (except blood pressure) and clinical scales compared with baseline (p<0.05). The QARP group also showed more significant improvement in the mMRC dyspnea scale (-1.8 [-2.1, -1.6], p=0.018) and modified Borg dyspnea scale (-3.7 [95% confidence intervals (CI) -4.3, -3.1], p=0.045). The duration of cough was 14.3 days (95% CI 12.6, 16.1, p=0.046), and the length of hospital stay was 18.5 days (95% CI 17.0, 20.0, p=0.042) in the QARP group, both of which were significantly reduced compared with the standard therapies group (p<0.05).

conclusionQARP plus standard therapies improved lung function and symptoms such as dyspnea and cough in patients with severe COVID-19 and shortened the length of hospital stay. Therefore, QARP may be considered an effective treatment option for patients with severe COVID-19.

trial registrationClinical Research Information Service Identifier: ChiCTR2000029994.

Indexed as

AcupressureCOVID-19Pulmonary functionQigongTelerehabilitation

Identifiers

PMID34733607
PMCPMC8553411
OpenAlexW3211218923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.