Evidence map›Paper›PMID 34733523›Full record

ReviewGastroenterology report2021

Gastroesophageal reflux disease: recent innovations in endoscopic assessment and treatment.

Sheng Chen, Feng Du, Changqing Zhong, Caifang Liu, Xiaoying Wang, Yan Chen, Gang Wang, Xiaopei Gao, Lu Zhang, Lianyong Li and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Gastroenterology report, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sheng ChenDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Feng DuDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Changqing ZhongDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Caifang LiuDepartment of Pediatrics, The First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, P. R. China.
Xiaoying WangDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Yan ChenDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Gang WangState Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Xiaopei GaoDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Lu ZhangDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Lianyong LiDepartment of Gastroenterology, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Wei WuState Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, PLA Strategic Support Force Characteristic Medical Center, Beijing, P. R. China.
Chinese PLA General Hospital · CNXi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innovations in endoscopy have brought about some impressive improvements in diagnosing and treating gastroesophageal reflux disease (GERD). GERD, as one of the most prevalent gastrointestinal disorders in the world, has always been on the cutting edge of endoscopic interventions. A primary diagnosis of GERD is based on symptoms and an initial trial of proton-pump inhibitor (PPI) therapy, which is devoid of adequately instructive value for therapeutic strategies. Endoscopy and optional biopsies can be used to directly observe and determine the abnormal structural and pathophysiological damage in the esophagus. The emergence of minimally invasive endoscopic therapy fills the gap between patients who are reluctant or insensitive to PPIs and candidates who are not indicated for surgical anti-reflux fundoplication. In this review, we discuss the utility of endoscopy and biopsy in patients with persistent GERD-related manifestations after proper medical anti-reflux treatment. Moreover, we portray a landscape of four current endoscopic GERD therapies and clarify the merits and disadvantages of each technique. Future research needs to concentrate on stratifying GERD patients based on personal conditions and elucidating the primary pathophysiology of GERD.

Indexed as

biopsyendoscopygastroesophageal reflux diseasetreatment

Identifiers

PMID34733523
PMCPMC8560030
OpenAlexW3205572304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.