Evidence map›Paper›PMID 34733373›Full record

ArticleThe open respiratory medicine journal2021

Association between Hypomagnesemia, COVID-19, Respiratory Tract and Lung Disease.

Gavino Faa, Luca Saba, Daniela Fanni, Goce Kalcev, Mauro Carta

Open access · diamondAbstract readEditorial
In one paragraph

Article in The open respiratory medicine journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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  10. Deciphering the immunoboosting potential of macro and micronutrients in COVID support therapy.Environmental science and pollution research international · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Gavino FaaDivision of Pathology, Department of Medical Sciences and Public Health, University Hospital San Giovanni di Dio, Cagliari, Italy.
Luca SabaDepartment of Medical Imaging, Azienda Ospedaliero Universitaria (AOU) of Cagliari-Polo di Monserrato, Cagliari, Italy.
Daniela FanniDivision of Pathology, Department of Medical Sciences and Public Health, University Hospital San Giovanni di Dio, Cagliari, Italy.
Goce KalcevInternational Ph.D. in Innovation Sciences and Technologies, University of Cagliari, Cagliari, Italy.
Mauro CartaDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
University of Cagliari · ITAzienda Ospedaliero-Universitaria Cagliari · ITNuovo Ospedale San Giovanni di Dio · ITTemple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complexity of COVID-19 is also related to the multiple molecular pathways triggered by SARS-CoV-2, which is able to cause type I pneumocyte death, trigger intravascular coagulation, interfere with the renin-angiotensin system, dysregulate iron metabolism, ending with the insurgence of a cytokine storm which may lead to death. Old adults with obesity, hypertension, and diabetes are among the high-risk category groups more prone to SARS-CoV-2 infection. Magnesium has been reported to play a major role both in physiology and in pathology, particularly in elderly people, regulating cytotoxic functions of natural killer (NK) cells and CD8+ T lymphocytes. In spite of the absence of controlled trials, the possibility of magnesium supplementation for supportive treatment in patients with COVID-19 should be encouraged. This could be useful in all phases of the COVID-19 disease.

Indexed as

COVID-19EffectsLung diseasesMagnesiumMagnesium deficiencyObesity

Identifiers

PMID34733373
PMCPMC8493831
OpenAlexW3192218187

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.