Evidence map›Paper›PMID 34733274›Full record

ArticleFrontiers in immunology2021

APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces

Louise Bjerkan, Ganesh Ram R Visweswaran, Arnar Gudjonsson, Geneviève M Labbé, Doris Quinkert, David J Pattinson, Heidi C L Spång, Simon J Draper, Bjarne Bogen, Ranveig Braathen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Louise BjerkanInstitute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Ganesh Ram R VisweswaranInstitute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Arnar GudjonssonInstitute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Geneviève M LabbéJenner Institute, University of Oxford, Oxford, United Kingdom.
Doris QuinkertJenner Institute, University of Oxford, Oxford, United Kingdom.
David J PattinsonJenner Institute, University of Oxford, Oxford, United Kingdom.
Heidi C L SpångInstitute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Simon J DraperJenner Institute, University of Oxford, Oxford, United Kingdom.
Bjarne BogenInstitute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Ranveig BraathenInstitute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOJenner Institute · GBUniversity of Oslo · NOUniversity of Oxford · GB

Funding

Wellcome Trust 106917/Z/15/Z
6 · The paper itself

Abstract

Targeted delivery of antigen to antigen presenting cells (APCs) is an efficient way to induce robust antigen-specific immune responses. Here, we present a novel DNA vaccine that targets the

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ProtozoanAntibody SpecificityAntigen-Presenting CellsAntigens, ProtozoanCarrier ProteinsDisease Models, AnimalEpitopesFemaleGene OrderGenetic VectorsImmunizationMalaria, FalciparumMalaria VaccinesMiceAntibodies, NeutralizingAntibodies, ProtozoanAntigens, ProtozoanCarrier ProteinsEpitopesMalaria VaccinesRH5 protein, Plasmodium falciparumVaccines, DNAantibody responsesAPC-targetingDNA vaccinesGIAmalariaPfRH5T cell responses

Identifiers

PMID34733274
PMCPMC8558525
OpenAlexW3207870908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.