Evidence map›Paper›PMID 34733271›Full record

ArticleFrontiers in immunology2021

Laura Massarenti, Christian Enevold, Dres Damgaard, Niels Ødum, Peter Garred, Morten Frisch, Miriam A Shelef, Søren Jacobsen, Claus Henrik Nielsen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  14. Autoantibodies against SUMO1-DHX35 in long-COVID.Journal of translational autoimmunity · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Laura MassarentiInstitute for Inflammation Research, Center for Rheumatology and Spine Diseases, Section 7521, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Christian EnevoldInstitute for Inflammation Research, Center for Rheumatology and Spine Diseases, Section 7521, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Dres DamgaardInstitute for Inflammation Research, Center for Rheumatology and Spine Diseases, Section 7521, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Niels ØdumLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Peter GarredLaboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Morten FrischDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Miriam A ShelefDepartment of Medicine, University of Wisconsin-Madison, Madison, WI, United States.
Søren JacobsenCopenhagen Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases, Section 4242, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Claus Henrik NielsenInstitute for Inflammation Research, Center for Rheumatology and Spine Diseases, Section 7521, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Copenhagen University Hospital · DKRigshospitalet · DKLEO Foundation · DKStatens Serum Institut · DKWilliam S. Middleton Memorial Veterans Hospital · US

Funding

PAD2 and PAD4 in Citrullination, Autoantibodies, and Rheumatoid ArthritisK08AR065500 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI SHELEF, MIRIAM ANNE · 2014 to 2018
$690k
NIAMS NIH HHS K08 AR065500
6 · The paper itself

Abstract

Peptidylarginine deiminases (PADs) catalyze citrullination, a post-translational modification playing a pathogenic role in anti-citrullinated protein antibody (ACPA)-positive rheumatoid arthritis (RA). The interplay between single nucleotide polymorphisms (SNPs) in the

Indexed as

Genetic Predisposition to DiseaseAdultAgedAged, 80 and overAnti-Citrullinated Protein AntibodiesArthritis, RheumatoidDenmarkFemaleHLA-DRB1 ChainsHumansMaleMiddle AgedPolymorphism, Single NucleotideProtein-Arginine Deiminase Type 4SmokingAnti-Citrullinated Protein AntibodiesHLA-DRB1*04 antigenHLA-DRB1 ChainsPADI4 protein, humanProtein-Arginine Deiminase Type 4anti-citrullinated proteins antibodies (ACPA)HLA-DRB1*04peptidylarginine deiminase (PAD)rheumatoid arthritissingle nucleotide polymorphism (SNP)

Identifiers

PMID34733271
PMCPMC8558474
OpenAlexW3206954497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.