Evidence map›Paper›PMID 34733130›Full record

ArticleAdvanced functional materials2021

Ultra-selective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques.

Mahsa Gifani, Devon J Eddins, Hisanori Kosuge, Yapei Zhang, Sesha L A Paluri, Timothy Larson, Nicholas Leeper, Leonore A Herzenberg, Sanjiv Sam Gambhir, Michael V McConnell and 2 more

Open access · greenAbstract read
In one paragraph

Article in Advanced functional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 52 citations in OpenAlex.

  1. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Review
  3. In Situ Synthesis of a Tumor Microenvironment-Activated Radiosensitizing CuAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Nanomedicine for Diagnosis and Treatment of Atherosclerosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  12. Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review.International journal of molecular sciences · 2023
    Review
  13. Review
  14. Nanomedicines for cardiovascular disease.Nature cardiovascular research · 2023
    Review
  15. Article
  16. Carbon Dots for the Treatment of Inflammatory Diseases: An Appraisal ofOxidative medicine and cellular longevity · 2023
    Review
  17. Review
  18. Review
  19. Advances in nanomaterial-based targeted drug delivery systems.Frontiers in bioengineering and biotechnology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Mahsa GifaniDepartment of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48824, USA.
Devon J EddinsDepartments of Medicine and Pediatrics, Lowance Center for Human Immunology, Emory University, Atlanta, GA 30322, USA.
Hisanori KosugeDivision of Cardiovascular Medicine and Vascular Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Yapei ZhangDepartment of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48824, USA.
Sesha L A PaluriDepartment of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48824, USA.
Timothy LarsonDepartments of Radiology, Bioengineering, and Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.
Nicholas LeeperDivision of Cardiovascular Medicine and Vascular Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Leonore A HerzenbergDepartment of Genetics, Stanford University, Stanford, CA 94305, USA.
Sanjiv Sam GambhirDepartments of Radiology, Bioengineering, and Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.
Michael V McConnellDivision of Cardiovascular Medicine and Vascular Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Eliver E B GhosnDepartments of Medicine and Pediatrics, Lowance Center for Human Immunology, Emory University, Atlanta, GA 30322, USA.
Bryan Ronain SmithDepartment of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48824, USA.
Michigan State University · USStanford Medicine · USStanford University · USEmory University · US

Funding

Small Animal ImagingP50CA114747 · NCI · STANFORD UNIVERSITY · PI MATIN, AC · 2005 to 2014
$18.2M
Macrophage-specific nanotherapy for breast cancerR01CA244491 · NCI · OHIO STATE UNIVERSITY · PI Bryan Ronain Smith · 2020 to 2026
$2.5M
Integrin-dependent modulation of macrophage functionR01AI123126 · NIAID · EMORY UNIVERSITY · PI GHOSN, ELIVER · 2016 to 2020
$2.3M
How do Nanoparticles Target Cancer? An In Vivo Experimental/Mathematical StudyK99CA160764 · NCI · STANFORD UNIVERSITY · PI SMITH, BRYAN RONAIN · 2011 to 2012
$348k
American Heart Association-American Stroke Association 18TPA34230113NCI NIH HHS K99 CA160764NCI NIH HHS P50 CA114747NCI NIH HHS R01 CA244491NIAID NIH HHS R01 AI123126
6 · The paper itself

Abstract

Disruption of vulnerable atherosclerotic plaques often leads to myocardial infarction and stroke, the leading causes of morbidity and mortality in the United States. A diagnostic method that detects high-risk atherosclerotic plaques at early stages could prevent these sequelae. The abundance of immune cells in the arterial wall, especially inflammatory Ly-6C

Indexed as

atherosclerosiscarbon nanotubesdiagnostic imagingflow cytometryimmunoimagingphotoacoustic imaging

Identifiers

PMID34733130
PMCPMC8559995
OpenAlexW3173262919

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.