Evidence map›Paper›PMID 34732941›Full record

ArticleJournal of applied polymer science2020

QCM-D assay for quantifying the swelling, biodegradation, and protein adsorption of intelligent nanogels.

John R Clegg, Catherine M Ludolph, Nicholas A Peppas

Abstract read
In one paragraph

Article in Journal of applied polymer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Multicharged Zwitterions form Superior Antifouling Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John R CleggDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton St., Stop C0800, Austin, Texas P. O. Box 78712.ORCID 0000-0002-7244-3041
Catherine M LudolphMcKetta Department of Chemical Engineering, The University of Texas at Austin, 107 W. Dean Keeton St., Stop C0800, Austin, Texas P. O. Box 78712.
Nicholas A PeppasDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton St., Stop C0800, Austin, Texas P. O. Box 78712.

Funding

Sensor arrays based on molecularly imprinted polymers for diagnosis of Sjogren's syndromeR01EB022025 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI ANSLYN, ERIC V., PEPPAS, NICHOLAS A · 2016 to 2019
$1.5M
NIBIB NIH HHS R01 EB022025
6 · The paper itself

Abstract

Environmentally responsive nanomaterials have been developed for drug delivery applications, in an effort to target and accumulate therapeutic agents at sites of disease. Within a biological system, these nanomaterials will experience diverse conditions which encompass a variety of solute identities and concentrations. In this study, we developed a new quartz crystal microbalance with dissipation (QCM-D) assay, which enabled the quantitative analysis of nanogel swelling, protein adsorption, and biodegradation in a single experiment. As a proof of concept, we employed this assay to characterize non-degradable and biodegradable poly(acrylamide-

Indexed as

biodegradabledrug delivery systemsstimuli-sensitive polymerssurfaces and interfacesswelling

Identifiers

PMID34732941
PMCPMC8562820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.