Evidence map›Paper›PMID 34732850›Full record

ArticleThe ISME journal2022

Mechanisms underlying interactions between two abundant oral commensal bacteria.

Dasith Perera, Anthony McLean, Viviana Morillo-López, Kaileigh Cloutier-Leblanc, Eric Almeida, Kiana Cabana, Jessica Mark Welch, Matthew Ramsey

Open access · hybridAbstract read
In one paragraph

Article in The ISME journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
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  6. Long-term continuous corrosion of 316L stainless steel byFrontiers in bioengineering and biotechnology · 2025
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  13. Spatial ecology ofMicrobiology spectrum · 2024
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dasith PereraThe University of Rhode Island, Kingston, RI, 02881, USA.
Anthony McLeanMarine Biological Laboratory, Woods Hole, MA, 02543, USA.
Viviana Morillo-LópezMarine Biological Laboratory, Woods Hole, MA, 02543, USA.
Kaileigh Cloutier-LeblancThe University of Rhode Island, Kingston, RI, 02881, USA.
Eric AlmeidaThe University of Rhode Island, Kingston, RI, 02881, USA.
Kiana CabanaThe University of Rhode Island, Kingston, RI, 02881, USA.
Jessica Mark WelchMarine Biological Laboratory, Woods Hole, MA, 02543, USA.
Matthew RamseyThe University of Rhode Island, Kingston, RI, 02881, USA. mramsey@uri.edu.ORCID http://orcid.org/0000-0001-7158-5120
University of Rhode Island · USMarine Biological Laboratory · US

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Bongsup P Cho · 2012 to 2026
$63.6M
Spatial Organization of the Oral MicrobiomeR01DE022586 · NIDCR · MARINE BIOLOGICAL LABORATORY · PI Jessica Leigh Mark Welch · 2013 to 2026
$8.7M
Mechanisms underlying spatial interaction in the oral microbiotaR01DE027958 · NIDCR · UNIVERSITY OF RHODE ISLAND · PI RAMSEY, MATTHEW · 2019 to 2023
$1.9M
NIDCR NIH HHS R01 DE022586NIDCR NIH HHS R01 DE027958NIGMS NIH HHS P20 GM103430United States Department of Agriculture | National Institute of Food and Agriculture (NIFA) 1017848
6 · The paper itself

Abstract

Complex polymicrobial biofilm communities are abundant in nature particularly in the human oral cavity where their composition and fitness can affect health. While the study of these communities during disease is essential and prevalent, little is known about interactions within the healthy plaque community. Here we describe interactions between two of the most abundant species in this healthy microbiome, Haemophilus parainfluenzae and Streptococcus mitis. We discovered that H. parainfluenzae typically exists adjacent to mitis group streptococci in vivo with which it is also positively correlated based on microbiome data. By comparing in vitro coculture data to ex vivo microscopy we revealed that this co-occurrence is density dependent and further influenced by H

Indexed as

Hydrogen PeroxideMicrobiotaBacteriaBiofilmsHumansStreptococcusHydrogen Peroxide

Identifiers

PMID34732850
PMCPMC8940909
OpenAlexW3208780794

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.