Evidence map›Paper›PMID 34732846›Full record

ArticleNature nanotechnology2021

The role and impact of polyethylene glycol on anaphylactic reactions to COVID-19 nano-vaccines.

P Bigini, M Gobbi, M Bonati, A Clavenna, M Zucchetti, S Garattini, G Pasut

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Nature nanotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 85 citations in OpenAlex.

  1. Towards mRNA therapeutics 2.0.Nature reviews. Drug discovery · 2026
    Review
  2. Poly(sarcosine) Lipid Synthesis From COMacromolecular rapid communications · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Charge-Stabilized Nanodiscs as a New Class of Lipid Nanoparticles.Advanced materials (Deerfield Beach, Fla.) · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

P BiginiIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy. paolo.bigini@marionegri.it.
M GobbiIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0003-1014-6225
M BonatiIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
A ClavennaIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
M ZucchettiIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
S GarattiniIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
G PasutPharmaceutical and Pharmacological Sciences Department, University of Padova, Padua, Italy. gianfranco.pasut@unipd.it.ORCID http://orcid.org/0000-0002-8754-0899
Mario Negri Institute for Pharmacological Research · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NanotechnologyAnaphylaxisCOVID-19COVID-19 VaccinesDrug HypersensitivityHumansPolyethylene GlycolsSARS-CoV-2VaccinationCOVID-19 VaccinesPolyethylene Glycols

Identifiers

PMID34732846
OpenAlexW3208010780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.