Evidence map›Paper›PMID 34732793›Full record

ArticleScientific reports2021

On-road driving impairment following sleep deprivation differs according to age.

Anna W T Cai, Jessica E Manousakis, Bikram Singh, Jonny Kuo, Katherine J Jeppe, Elly Francis-Pester, Brook Shiferaw, Caroline J Beatty, Shantha M W Rajaratnam, Michael G Lenné and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07434921 (TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE, ©" AMONG COLLEGE STUDENTS), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07434921 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Testing an mtm theory-based intervention on reducing drowsy driving behavior, "stay awake, stay alive, ©" among college students: an educational randomized controlled trial

TypeinterventionalSponsorUniversity of Nevada, Las VegasRan2026 to 2026Enrolled72ConditionsDrowsiness, Sleep Deprivation, FatigueArmsMTM Theory based intervention, Standard AAA Knowledge based
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. PERCLOS-based technologies for detecting drowsiness: current evidence and future directions.Sleep advances : a journal of the Sleep Research Society · 2023
    Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna W T CaiTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Jessica E ManousakisTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Bikram SinghTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Jonny KuoSeeing Machines, Fyshwick, ACT, 2609, Australia.
Katherine J JeppeTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Elly Francis-PesterTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Brook ShiferawSeeing Machines, Fyshwick, ACT, 2609, Australia.
Caroline J BeattyTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Shantha M W RajaratnamTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Michael G LennéSeeing Machines, Fyshwick, ACT, 2609, Australia.
Mark E HowardTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia.
Clare AndersonTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, 3800, Australia. clare.anderson@monash.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired driving performance due to sleep loss is a major contributor to motor-vehicle crashes, fatalities, and serious injuries. As on-road, fully-instrumented studies of drowsy driving have largely focused on young drivers, we examined the impact of sleep loss on driving performance and physiological drowsiness in both younger and older drivers of working age. Sixteen 'younger' adults (M = 24.3 ± 3.1 years [21-33 years], 9 males) and seventeen 'older' adults (M = 57.3 ± 5.2, [50-65 years], 9 males) undertook two 2 h drives on a closed-loop track in an instrumented vehicle with a qualified instructor following (i) 8 h sleep opportunity the night prior (well-rested), and (ii) after 29-h of total sleep deprivation (TSD). Following TSD, both age groups displayed increased subjective sleepiness and lane departures (p < 0.05), with younger drivers exhibiting 7.37 × more lane departures, and 11 × greater risk of near crash events following sleep loss. While older drivers exhibited a 3.5 × more lane departures following sleep loss (p = 0.008), they did not have a significant increase in near-crash events (3/34 drives). Compared to older adults, younger adults had 3.1 × more lane departures (p = < 0.001), and more near crash events (79% versus 21%, p = 0.007). Ocular measures of drowsiness, including blink duration, number of long eye closures and PERCLOS increased following sleep loss for younger adults only (p < 0.05). These results suggest that for older working-aged adults, driving impairments observed following sleep loss may not be due to falling asleep. Future work should examine whether this is attributed to other consequences of sleep loss, such as inattention or distraction from the road.

Indexed as

Accidents, TrafficAutomobile DrivingSleep DeprivationAdultAgedAge FactorsBehaviorBlinkingCircadian RhythmDisorders of Excessive SomnolenceFemaleHumansMaleMiddle AgedRiskSleep

Identifiers

PMID34732793
PMCPMC8566466

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.