Evidence map›Paper›PMID 34732576›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Cognitive deficits and impaired hippocampal long-term potentiation in K

Shaul Yahil, David F Wozniak, Zihan Yan, Steven Mennerick, Maria S Remedi

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Bayliss-Starling Prize Lecture: KThe Journal of physiology · 2025
    Article
  3. ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Personalized Therapeutics for KAnnual review of pharmacology and toxicology · 2023
    Review
  7. KFunction (Oxford, England) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shaul YahilDivision of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
David F WozniakDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0003-3301-740X
Zihan YanDivision of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Steven MennerickDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Maria S RemediDivision of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110; mremedi@wustl.edu.ORCID 0000-0003-2048-472X
Washington University in St. Louis · US

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Beta-Cell Exhaustion and Glucotoxicity in DiabetesR01DK123163 · NIDDK · WASHINGTON UNIVERSITY · PI Maria Sara Remedi · 2020 to 2026
$2.8M
GABAA RECEPTOR POPULATIONS IN HIPPOCAMPUS AND THALAMUSR01MH123748 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2021 to 2025
$2.4M
BETA-CELL EXHAUSTION AND GLUCOTOXICITY IN DIABETESR01DK098584 · NIDDK · WASHINGTON UNIVERSITY · PI REMEDI, MARIA SARA · 2013 to 2017
$1.7M
Beta-Cell Exhaustion and Glucotoxicity in DiabetesR56DK098584 · NIDDK · WASHINGTON UNIVERSITY · PI REMEDI, MARIA SARA · 2019 to 2019
$117k
NICHD NIH HHS P50 HD103525NICHD NIH HHS U54 HD087011NIDDK NIH HHS R01 DK098584NIDDK NIH HHS R01 DK123163NIDDK NIH HHS R56 DK098584NIMH NIH HHS R01 MH123748
6 · The paper itself

Abstract

ATP-sensitive potassium (K

Indexed as

AnimalsCognition DisordersDiabetes MellitusDisease Models, AnimalEpilepsyFemaleGain of Function MutationHippocampusInfant, Newborn, DiseasesKATP ChannelsLearning DisabilitiesLong-Term PotentiationMaleMemory DisordersMice, TransgenicMotor DisordersKATP ChannelsSulfonylurea CompoundsbehaviorcognitionDENDelectrophysiologyKATP

Identifiers

PMID34732576
PMCPMC8609313
OpenAlexW3211039986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.