Evidence map›Paper›PMID 34732559›Full record

ArticleSaudi medical journal2021

The effect of cerium oxide on lung injury following lower extremity ischemia-reperfusion injury in rats under desflurane anesthesia.

Aycan Ozdemirkan, Aysegul Kucuk, Isin Gunes, Mustafa Arslan, Aydin Tuncay, Volkan Sivgin, Saban C Sezen, Hakan Boyunaga

Abstract read
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In one paragraph

Article in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The Effect of Cerium Oxide (CeOMedicina (Kaunas, Lithuania) · 2024
    Article
  4. Effects of cerium oxide (CeOBMC anesthesiology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aycan OzdemirkanFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Aysegul KucukFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Isin GunesFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Mustafa ArslanFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Aydin TuncayFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Volkan SivginFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Saban C SezenFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
Hakan BoyunagaFrom the Department of Anesthesiology and Reanimation (Ozdemirkan, Arslan, Sivgin), Gazi University Faculty of Medicine, from the Department of Medical Biochemistry (Boyunaga), Ankara Medipol University, Ankara, from the Department of Physiology (Kucuk), Faculty of Medicine, Kütahya Health Science University, Kütahya, from the Department of Anesthesiology and Reanimation (Gunes), from the Department of Cardiovascular Surgery (Tuncay), Faculty of Medicine, Erciyes University, Kayseri, and from the Department of Histology and Embryology (Sezen), Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the effects of desflurane and cerium oxide (CO) on lung tissue following ischemia-reperfusion injury (IRI).

methodsExperiments were conducted in Gazi University Animal Laboratory, Ankara, Turkey. Thirty rats were divided into 5 groups: control (C), IRI, IRI-CO, IRI-desflurane (IRID), IRI-CO-desflurane (IRICOD). Cerium oxide was given intraperitoneally. Lower extremity IRI was induced. Desflurane was applied during IRI. Lung histopathological examinations and serum biochemical analyses were performed.

resultsSerum nitric oxide (NO) and malondialdehyde (MDA) levels were higher in group IRI (

conclusionIntraperitoneal CO with desflurane, reduced oxidative stress and corrected the damage in lung. Cerium oxide given before and desflurane given during IRI have been shown to have protective effects on lung damage in rats.

Indexed as

AnesthesiaLung InjuryReperfusion InjuryAnimalsCeriumDesfluraneLower ExtremityRatsceric oxideCeriumDesfluraneceriumdesfluraneischemia-reperfusion injurylung injury

Identifiers

PMID34732559
PMCPMC9149742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.