Evidence map›Paper›PMID 34732550›Full record

ArticleSaudi medical journal2021

Causes, timing, and modes of death in a tertiary pediatric intensive care unit: Five years' experience.

Ayman Al-Eyadhy, Mohamad-Hani Temsah, Gamal M Hasan, Mohammed Almazyad, Ali A Alhaboob, Majed Alabdulhafid, Fahad Alsohime, Ahmed S Alzahrani, Abdullah M Alammari, Faisal S Abunohaiah and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Multinational Pediatric Critical Care Research in the Arab Gulf Region across 35 Pediatric Intensive Care Units: Ethical Approval Timelines and Lessons Learned.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026
    Article
  5. Infant Intensive Care Unit: Is it Time to Change?Indian journal of pediatrics · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ayman Al-EyadhyFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Mohamad-Hani TemsahFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Gamal M HasanFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Mohammed AlmazyadFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Ali A AlhaboobFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Majed AlabdulhafidFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Fahad AlsohimeFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Ahmed S AlzahraniFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Abdullah M AlammariFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Faisal S AbunohaiahFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Nawaf F AlfawzanFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
Suhail S AlghamdiFrom the College of Medicine (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime, Alzahrani, Alammari, Abunohaiah, Alfawzan, Alghamdi), King Saud University; from the Department of Pediatric (Al-Eyadhy, Temsah, Almazyad, Alhaboob, Alabdulhafid, Alsohime), Pediatric Intensive Care Unit, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Faculty of Medicine, Assiut University, Assiut, Egypt, and from the Department of Pediatrics (Hasan), Pediatric Intensive Care Unit, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates.
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo identify the causes, modes, and timing of death in a tertiary pediatric intensive care unit (PICU).

methodsThis is a retrospective data analysis of patients older than 48 hours and younger than 15 years who died in the PICU over a 5-year period from January 2012 until December 2016 at a tertiary hospital in Riyadh, Saudi Arabia.

resultsThere were 101 deaths out of 2295 admissions, representing average crude mortality rate of 4.4%. Sepsis was the most common cause of death in 31 patients (30.7%), followed by lower respiratory tract infections in 19 (18.8%), and cardiac diseases in 12 (11.9%). Failed cardiopulmonary resuscitation was the most common mode of death in 51 patients (50.5%), followed by withholding life-sustaining treatment in 43 (42.6%), and brain death in 7 (6.9%). Although more deaths occurred during after hours (n=70; 69.3%), there was no significant correlation between mode of death and working hours vs. after hours (

conclusionInfections remain a significant cause of death in the PICU. Further improvement of prevention programs and early therapy of severe infections could lower pediatric mortality. This report highlights the need for enhancing palliative care programs. The low rate of brain death diagnoses warrants further investigation.

Indexed as

Cardiopulmonary ResuscitationIntensive Care Units, PediatricBrain DeathChildHospitalizationHumansRetrospective Studiescauses of deathinfectionsmode of deathpediatricsSaudi

Identifiers

PMID34732550
PMCPMC9149741
OpenAlexW3208653593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.