Evidence map›Paper›PMID 34732535›Full record

ArticleeNeuro

TRPM4 Contributes to Subthreshold Membrane Potential Oscillations in Multiple Mouse Pacemaker Neurons.

Keyong Li, Yingtang Shi, Elizabeth C Gonye, Douglas A Bayliss

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The physiological role of TRP channels in sleep and circadian rhythm.Journal of cellular and molecular medicine · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Keyong LiDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908.
Yingtang ShiDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908.
Elizabeth C GonyeDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908.
Douglas A BaylissDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908 bayliss@virginia.edu.ORCID 0000-0002-5630-2572
University of Virginia · US

Funding

Cellular/Molecular Mechanisms of Respiratory Neuronal ChemosensitivityR01HL108609 · NHLBI · UNIVERSITY OF VIRGINIA · PI Douglas A. Bayliss · 2011 to 2026
$6.5M
NHLBI NIH HHS R01 HL108609
6 · The paper itself

Abstract

Select neuronal populations display steady rhythmic neuronal firing that provides tonic excitation to drive downstream networks and behaviors. In noradrenergic neurons of the locus coeruleus (LC), circadian neurons of the suprachiasmatic nucleus (SCN), and CO

Indexed as

TRPM Cation ChannelsAction PotentialsAnimalsBiological ClocksCalcium Channels, L-TypeCentral Pattern GeneratorsMembrane PotentialsMiceMice, Inbred CBANeuronsCalcium Channels, L-TypeTRPM4 protein, mouseTRPM Cation Channelscalcium-dependentcationic currentICaNtonic firingTRP channelswaveform command

Identifiers

PMID34732535
PMCPMC8607911
OpenAlexW3210571988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.