Evidence map›Paper›PMID 34732502›Full record

ArticleBMJ open2021

Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD)? protocol for a feasibility randomised controlled trial.

Mohsan Subhani, Katy A Jones, Kirsty Sprange, Stefan Rennick-Egglestone, Holly Knight, Joanne R Morling, Doyo G Enki, Andrew Wragg, Stephen D Ryder

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mohsan SubhaniNottingham Digestive Diseases Biomedical Research Centre (NDDC), School of Medicine, University of Nottingham, Nottingham, UK mohsan.subhani@nottingham.ac.uk.ORCID 0000-0001-8739-7263
Katy A JonesAcademic Unit of Mental Health and Clinical Neuroscience, School of Medicine, C24 Institute of Mental Health, University of Nottingham, Nottingham, UK.
Kirsty SprangeNottingham Clinical Trials Research Unit, University of Nottingham, Nottingham, UK.ORCID 0000-0001-6443-7242
Stefan Rennick-EgglestoneSchool of Health Sciences,Institute of Mental Health, University of Nottingham, Nottingham, UK.
Holly KnightDivision of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.ORCID 0000-0002-4602-3238
Joanne R MorlingNottingham Digestive Diseases Biomedical Research Centre (NDDC), School of Medicine, University of Nottingham, Nottingham, UK.
Doyo G EnkiSchool of Medicine, University of Nottingham, Nottingham, UK.
Andrew WraggNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
Stephen D RyderNottingham Digestive Diseases Biomedical Research Centre (NDDC), School of Medicine, University of Nottingham, Nottingham, UK.
University of Nottingham · GBNottingham University Hospitals NHS Trust · GB

Funding

Medical Research Council MR/P008348/1
6 · The paper itself

Abstract

introductionHeavy drinkers in contact with alcohol services do not routinely have access to testing to establish the severity of potential liver disease. Transient elastography by FibroScan can provide this information. A recent systematic review suggested providing feedback to patients based on markers of liver injury can be an effective way to reduce harmful alcohol intake. This randomised control trial (RCT) aims to establish the feasibility of conducting a larger national trial to test the effectiveness of FibroScan advice and Alcohol Recovery Video Stories (ARVS) in changing high-risk drinking behaviour in community alcohol services common to UK practice. METHODS AND ANALYSIS: This feasibility trial consists of three work packages (WP). ETHICS AND DISSEMINATION: This trial received favourable ethical approval from the West of Scotland Research Ethics Service (WoSRES) on 20 January 2021, REC reference: 20/WS/0179. Results will be submitted for publication to a peer-reviewed journal. TRIAL REGISTRATION NUMBER: ISRCTN16922410.

Indexed as

KnowledgeLiver CirrhosisDrinking BehaviorFeasibility StudiesHumansRandomized Controlled Trials as TopicScotlandgastroenterologyhepatologypublic health

Identifiers

PMID34732502
PMCPMC8572412
OpenAlexW3210517263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.