ArticleBMJ open diabetes research & care2021
Secular incidence trends and effect of population aging on mortality due to type 1 and type 2 diabetes mellitus in China from 1990 to 2019: findings from the Global Burden of Disease Study 2019.
Article in BMJ open diabetes research & care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05783700 (Identification of Biomarkers for the Study of Sarcopenia and Its Evolution in Diabetic Patients.), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identification of Biomarkers for the Study of Sarcopenia and Its Evolution in Diabetic Patients.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Influencing factors of stroke in patients with type 2 diabetes: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Burden of cancer in China from 1990 to 2023 and projections to 2050.Science China. Life sciences · 2026Article
- Protein arginine methyltransferases as metabolic regulators: many roles beyond cancer.Science China. Life sciences · 2026Review
- East Asia and high-income Asia Pacific burden of diabetes mellitus from 1990 to 2023.iScience · 2026Article
- Observational
- Analysis and prediction of the trends in diabetes mellitus mortality in Chinese residents from 2008 to 2021.Archives of public health = Archives belges de sante publique · 2026Article
- Global burden and projections of cardiometabolic diseases attributable to high alcohol use: a comparative risk assessment based on the GBD 2021 study.Frontiers in nutrition · 2026Article
- Unmasking Type 2 Diabetes in an Aging Mexico: Trends and Disparities by Sex and State-Level From the GBD 2021 Study.Journal of diabetes research · 2026Article
- Article
- Incidence, prevalence, and burden of type 2 diabetes in China: Trend and projection from 1990 to 2050.Chinese medical journal · 2025Article
- The national and provincial prevalence and non-fatal burdens of diabetes in China from 2005 to 2023 with projections of prevalence to 2050.Military Medical Research · 2025Article
- Transitioning to adult care in youth-onset diabetes: a scoping review of socio-ecological factors in youth-onset type 2 diabetes compared to type 1 diabetes.BMC public health · 2025Article
- The combined effect of CRP and blood pressure on the risk of mortality in patients with type 2 diabetes.Scientific reports · 2025Article
- Pregestational Diabetes and Adverse Pregnancy Results: A Mendelian Randomization Study.Archives of Iranian medicine · 2025Article
- Burden of type 2 diabetes due to high body mass index in different SDI regions and projections of future trends: insights from the Global Burden of Disease 2021 study.Diabetology & metabolic syndrome · 2025Article
- Diabetes in China: epidemiology, pathophysiology and multi-omics.Nature metabolism · 2025 · on this mapReview
- Global epidemiology and burden of type 2 diabetes in adults aged 55 and older: insights from 1990 to 2021.Therapeutic advances in endocrinology and metabolism · 2025Article
- Epidemiology and temporal trends of childhood type 1 diabetes in China: an analysis of the GBD 2021.Frontiers in endocrinology · 2025Article
- Effect of a nursing intervention based on nutritional support on biochemical parameters and quality of life in patients with hyperthyroidism combined with diabetes mellitus.Frontiers in endocrinology · 2025Article
- Spatiotemporal trends of Type 2 diabetes due to low physical activity from 1990 to 2019 and forecasted prevalence in 2050: A Global Burden of Disease Study 2019.The journal of nutrition, health & aging · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDiabetes and population aging have become public health issues of global concern. The secular incidence trends and the impact of population aging on mortality due to type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in China remain unclear. RESEARCH DESIGN AND
methodsThe incidence and mortality rates of T1DM and T2DM from 1990 to 2019 were abstracted from the Global Burden of Disease Study (GBD) 2019 database. Joinpoint regression and age-period-cohort models were used to calculate the average annual percentage change and relative risk (RR), respectively. A decomposition method was used to attribute changes in total deaths to population growth, population aging, and the mortality rate change from 1990 to 2019.
resultsFrom 1990 to 2019, the T1DM age-standardized incidence rate (ASIR) increased by 2.01% (95% CI 1.78% to 2.23%) in males and 1.70% (1.61% to 1.80%) in females, and the T1DM age-standardized mortality rate (ASMR) decreased by 1.96% (-2.22% to -1.71%) in males and 4.02% (-4.48% to -3.57%) in females. The T2DM ASIR increased by 0.81% (0.62% to 0.99%) in males and 0.37% (0.16% to 0.58%) in females, and the T2DM ASMR increased by 1.06% (0.87% to 1.25%) in males and decreased by 0.24% (-0.54% to 0.07%) in females. Compared with 1990, the proportions of deaths attributed to population aging ranged from 18.85% (T1DM) to 148.21% (T2DM) for males and 29.80% (T1DM) to 118.82% (T2DM) for females in 2019.
conclusionsThe T1DM and T2DM incidence rates continually increased in China, particularly among young individuals. T1DM-related mortality decreased, while T2DM-related mortality increased in males. Population aging might be associated with a substantial change in the number of deaths from 1990 to 2019. To address the increase in T2DM-related deaths due to population aging, policymakers should promote aging-related health research and implement proven, cost-effective T2DM interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.