Evidence map›Paper›PMID 34732338›Full record

ArticleJournal of affective disorders2022

The COVID-19 pandemic in Italy: Depressive symptoms immediately before and after the first lockdown.

Emanuela Medda, Virgilia Toccaceli, Antonella Gigantesco, Angelo Picardi, Corrado Fagnani, Maria Antonietta Stazi

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emanuela MeddaCenter of Reference for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy. Electronic address: emanuela.medda@iss.it.
Virgilia ToccaceliCenter of Reference for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy.
Antonella GigantescoCenter of Reference for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy.
Angelo PicardiCenter of Reference for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy.
Corrado FagnaniCenter of Reference for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy.
Maria Antonietta StaziCenter of Reference for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy.
Istituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundItaly was one of the first countries to be heavily hit by the spread of the new Coronavirus. Longitudinal studies are needed to investigate the real effect of COVID-19 on adult mental health. The Italian Twin Registry carried out a study to investigate, over time, the course of depressive symptoms in the general population.

methodsThe study relies on data collected just before the beginning (February 2020) and the end (June 2020) of the first lockdown. Symptoms of depression were assessed using the Patient Health Questionnaire, and total scores or categorized depression scores were considered in the analyzes.

resultsA total of 1690 adult twins were recruited. The study showed a mean depression score of 1.11 immediately before lockdown and 1.20 immediately after, with an overall prevalence of depressive symptoms increasing from 33.6 to 38.9%. Depressive symptoms immediately after the restriction period were associated with Covid-19 symptoms affecting households, financial problems due to the pandemic and poor social support. Independently of the baseline risk of depressive symptoms, we observed an increased risk among younger and less educated people. Compared to the pre-lockdown period, women and middle-aged people also were found to be at greater risk of developing depressive symptoms. LIMITATIONS: Possible participation bias and residual selection bias.

conclusionsThe study shows that the COVID-19 pandemic was associated with an increased depressive symptomatology and that, in such health emergency times, the most vulnerable persons are young adults, women, and those living in a socially, culturally, or economically disadvantaged environment.

Indexed as

COVID-19AnxietyCommunicable Disease ControlDepressionFemaleHumansItalyMiddle AgedPandemicsSARS-CoV-2Young AdultCOVID-19DepressionPHQ-2Twin

Identifiers

PMID34732338
PMCPMC8557388
OpenAlexW3209485650

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.