Evidence map›Paper›PMID 34732305›Full record

ReviewInternational journal of biological macromolecules2021

Immunology and controlling of coronaviruses; the current enemy for humanity: A review.

Sarah I Othman, Mohamed A Nayel, Maha Abdulla Alwaele, Haifa Al Fassam, Gasem Mohammad Abu-Taweel, Naif Ghazi Altoom, Ahmed M Almalki, Ahmed A Allam, Asma M Alturki, Rehan M El-Shabasy

Open access · greenAbstract readReview
In one paragraph

Review in International journal of biological macromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Transfer factors peptides (Imuno TFFrontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Sarah I OthmanBiology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia. Electronic address: sialothman@pnu.edu.sa.
Mohamed A NayelDepartment of Animal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, University of Sadat City, Sadat City 32897, Menoufia, Egypt.
Maha Abdulla AlwaeleBiology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Haifa Al FassamBiology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Gasem Mohammad Abu-TaweelDepartment of Biology, College of Science, Jazan University, P.O. Box 2079, Jazan 45142, Saudi Arabia.
Naif Ghazi AltoomDepartment of Biology, King Khalid Military Academy, Riyadh 14625, Saudi Arabia.
Ahmed M AlmalkiZoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Ahmed A AllamDepartment of Zoology, Faculty of Science, Beni-suef University, Beni-suef 65211, Egypt. Electronic address: ahmed.aliahmed@science.bsu.edu.eg.
Asma M AlturkiDepartment of Chemistry, Faculty of Science, University of Tabuk, Saudi Arabia.
Rehan M El-ShabasyDepartment of Chemistry, Faculty of Science, Menoufia University, 32512 Shebin El-Kom, Egypt. Electronic address: elshabasy1010@gmail.com.
Princess Nourah bint Abdulrahman University · SABeni-Suef University · EGJazan University · SAKing Saud University · SAMenoufia University · EGRiyadh Armed Forces Hospital · SAUniversity of Sadat City · EGUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Severe Acute Respiratory Syndrome-related Coronavirus 2 (COVID-19 or SARS-CoV-2) epidemic is professed as world disaster producing a worrying increasing mortality, particularly amongst vulnerable humans worldwide. Whether COVID-19 has a strong ability for acceptable genetic flexibility that amended for breaking immune responses quickly, it is critical to understand the adaptation mechanism between viruses and hosts that allows individuals to follow viral development. This can contribute to finding the appropriate treatment to combat the epidemic. However, the present information about viral adaptation mechanisms in hosts is still insufficient, and future investigations may reveal the unknown. Mutations and genetic variations are naturally occurring; however, the current knowledge about their mechanism and pathways still has many secrets. The present review also provides insights into the immune system, immunological memory, and the development of the COVID-19 vaccine. Other fighting methods against COVID-19 are also highlighted. The potential of antibodies, natural metabolites, and current suggest vaccines were applied to the face of this new threat.

Indexed as

COVID-19COVID-19 VaccinesImmunologic MemoryHost-Pathogen InteractionsHumansSARS-CoV-2COVID-19 VaccinesCOVID-19Immune systemSARS-COV-2Vaccine

Identifiers

PMID34732305
PMCPMC8557928
OpenAlexW3211214098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.