ArticleArchives of craniofacial surgery2021
Anterior skull base reconstruction using an anterolateral thigh free flap.
Article in Archives of craniofacial surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of Free Flaps in the Reconstruction of the Ventral Skull Base: A Systematic Literature Review.Head & neck · 2026Pooled it
- Comparison of Clinical Outcomes Between Transcranial and Transmaxillary Free Flap Insets in Anterior Skull Base Reconstruction.Plastic and reconstructive surgery. Global open · 2026Article
- [Application of iceberg theory in the diagnosis and treatment of refractory wounds at the surgical site after craniotomy].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025Article
- Perforating patterns of cutaneous perforator vessels in anterolateral thigh flaps for head and neck reconstruction and clinical outcomes.Archives of craniofacial surgery · 2022Article
- Current concepts of neurofibromatosis type 1: pathophysiology and treatment.Archives of craniofacial surgery · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundGaleal or temporalis muscle flaps have been traditionally used to reconstruct skull base defects after tumor removal. Unfortunately, these flaps do not provide sufficient vascularized tissue for a dural seal in extensive defects. This study describes the successful coverage of large skull base defects using anterolateral thigh (ALT) free flaps.
methodsThis retrospective study included five patients who underwent skull base surgery between June 2018 and June 2021. Reconstruction was performed using an ALT free flap to cover defects that included the intracranial space and extended to the frontal sinus and cribriform plate.
resultsThere were no major complications, such as ascending infections or cerebrospinal leakage. Postoperative magnetic resonance imaging showed that the flaps were well-maintained in all patients.
conclusionSuccessful reconstruction was performed using ALT free flaps for large anterior skull base defects. In conclusion, the ALT free flap is an effective option for preventing communication between the nasal cavity and the intracranial space.
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