Evidence map›Paper›PMID 34731613›Full record

ArticleCell reports2021

Quantal Ca

Ana M Rossi, Andrew M Riley, Geneviève Dupont, Taufiq Rahman, Barry V L Potter, Colin W Taylor

Abstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. From IP3RPEP6 Inhibition of IPCellular and molecular life sciences : CMLS · 2025
    Review
  2. Review
  3. Quantal Properties of Voltage-Dependent CaThe Journal of membrane biology · 2024
    Article
  4. Tumor-specific cholinergic CD4Nature cancer · 2023
    Article
  5. Dissociation of inositol 1,4,5-trisphosphate from IPThe Journal of biological chemistry · 2023
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana M RossiDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK. Electronic address: amr50@cam.ac.uk.
Andrew M RileyDrug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
Geneviève DupontUnité de Chronobiologie Théorique, Faculté des Sciences, CP231 Université Libre de Bruxelles (ULB), Boulevard du Triomphe, 1050 Brussels, Belgium.
Taufiq RahmanDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK.
Barry V L PotterDrug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
Colin W TaylorDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK. Electronic address: cwt1000@cam.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/P005330/1Medical Research Council MR/T028378/1Wellcome Trust
6 · The paper itself

Abstract

Inositol 1,4,5-trisphosphate receptors (IP

Indexed as

AnimalsCalciumCalcium SignalingChickensDrug Partial AgonismEndoplasmic ReticulumHEK293 CellsHumansInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsInositol PhosphatesTime FactorsCalciumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate Receptorsinositol 2,4,5-trisphosphateInositol PhosphatesCa(2+) signalingendoplasmic reticulumintracellular Ca(2+) storesIP(3) receptorIP(3) receptor antagonistpartial agonistquantal Ca(2+) releasereceptor inactivation

Identifiers

PMID34731613
PMCPMC8578705

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.