Evidence map›Paper›PMID 34731465›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Fighting COVID-19 with Artificial Intelligence.

Stefania Monteleone, Tahsin F Kellici, Michelle Southey, Michael J Bodkin, Alexander Heifetz

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Accelerating COVID-19 Drug Discovery with High-Performance Computing.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefania MonteleoneEvotec (UK) Ltd., Abingdon, Oxfordshire, UK. stefania.monteleone@evotec.com.
Tahsin F KelliciEvotec (UK) Ltd., Abingdon, Oxfordshire, UK.
Michelle SoutheyEvotec (UK) Ltd., Abingdon, Oxfordshire, UK.
Michael J BodkinEvotec (UK) Ltd., Abingdon, Oxfordshire, UK.
Alexander HeifetzEvotec (UK) Ltd., Abingdon, Oxfordshire, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of vaccines for the treatment of COVID-19 is paving the way for new hope. Despite this, the risk of the virus mutating into a vaccine-resistant variant still persists. As a result, the demand of efficacious drugs to treat COVID-19 is still pertinent. To this end, scientists continue to identify and repurpose marketed drugs for this new disease. Many of these drugs are currently undergoing clinical trials and, so far, only one has been officially approved by FDA. Drug repurposing is a much faster route to the clinic than standard drug development of novel molecules, nevertheless in a pandemic this process is still not fast enough to halt the spread of the virus. Artificial intelligence has already played a large part in hastening the drug discovery process, not only by facilitating the selection of potential drug candidates but also in monitoring the pandemic and enabling faster diagnosis of patients. In this chapter, we focus on the impact and challenges that artificial intelligence has demonstrated thus far with respect to drug repurposing of therapeutics for the treatment of COVID-19.

Indexed as

Artificial IntelligenceCOVID-19 Drug TreatmentDrug DiscoveryDrug RepositioningAnimalsAntiviral AgentsCOVID-19Host-Pathogen InteractionsHumansMachine LearningMolecular StructureSARS-CoV-2Structure-Activity RelationshipAntiviral AgentsArtificial intelligenceCOVID-19Drug repurposingMachine learningSARS-CoV-2

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.