Evidence map›Paper›PMID 34731317›Full record

ArticleMikrochimica acta2021

Carboxylic acid-tethered polyaniline as a generic immobilization matrix for electrochemical bioassays.

Amarnath Chellachamy Anbalagan, Shilpa N Sawant

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Amarnath Chellachamy AnbalaganChemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400085, India.
Shilpa N SawantChemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400085, India. stawde@barc.gov.in.
Bhabha Atomic Research Centre · INHomi Bhabha National Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyaniline (PANI) was functionalized by thiol-ene click chemistry to obtain carboxylic acid-tethered polyaniline (PCOOH). The versatility of PCOOH as an immobilization matrix was demonstrated by constructing four different biosensors for detection of metabolites and cancer biomarker. Immobilization efficiency of PCOOH was investigated by surface plasmon resonance and fluorescence microscopic analysis which revealed dense immobilization of biomolecules on PCOOH as compared to conventional PANI. A sandwich electrochemical biosensor was constructed using PCOOH for detection of liver cancer biomarker, α-fetoprotein (AFP). The sensor displayed sensitivity of 15.24 µA (ng mL

Indexed as

alpha-FetoproteinsAniline CompoundsAntibodies, ImmobilizedArmoraciaBiomarkers, TumorBiosensing TechniquesCarboxylic AcidsElectrochemical TechniquesEnzymes, ImmobilizedGlucoseGlucose OxidaseHorseradish PeroxidaseHumansHydrogen PeroxideLimit of DetectionReproducibility of ResultsAFP protein, humanalpha-FetoproteinsAniline CompoundsAntibodies, ImmobilizedBiomarkers, TumorCarboxylic AcidsEnzymes, ImmobilizedGlucoseGlucose OxidaseHorseradish PeroxidaseHydrogen PeroxidepolyanilineUrate OxidaseUric AcidCancer biomarkerCyclic voltammetryElectroactivityElectrochemical biosensorImmobilizationPolyaniline

Identifiers

PMID34731317
OpenAlexW3211224590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.