Evidence map›Paper›PMID 34731314›Full record

ArticleMikrochimica acta2021

An electrochemical aptasensor for Mycobacterium tuberculosis ESAT-6 antigen detection using bimetallic organic framework.

Jiaojiao Xie, Zhaode Mu, Bin Yan, Jie Wang, Jing Zhou, Lijuan Bai

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. (Cu-S)Mikrochimica acta · 2026
    Article
  2. Zirconium-based metal-organic frameworks for pathogen detection.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Review
  3. Review
  4. Article
  5. Biosensors; nanomaterial-based methods in diagnosing ofJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiaojiao Xie *Chongqing Research Center for Pharmaceutical Engineering, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Zhaode Mu *Research Center for Pharmacodynamic Evaluation Engineering Technology of Chongqing, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Bin YanThe Eighth Middle School of Chongqing, Chongqing, 400030, People's Republic of China.
Jie WangResearch Center for Pharmacodynamic Evaluation Engineering Technology of Chongqing, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jing ZhouChongqing Research Center for Pharmaceutical Engineering, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Lijuan BaiChongqing Research Center for Pharmaceutical Engineering, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, People's Republic of China. bailijua88@126.com.
Chongqing Medical University · CN

Funding

ba yu scholar program, china YS2019020chongqing talent program, china CQYC202005015national natural science foundation of china 81601856national natural science foundation of china 82072378
6 · The paper itself

Abstract

A label-free electrochemical aptasensor is reported for sensitive detection of the 6-kDa early secreted antigenic target (ESAT-6). For the first time, the bimetallic organic framework (b-MOF) of Zr-MOF-on-Ce-MOF was decorated with nitrogen-doped graphene (NG) and applied as the matrix for electroactive toluidine blue (Tb) to form the NG@Zr-MOF-on-Ce-MOF@Tb nanohybrid. The prepared nanohybrid with excellent hydrophilicity, dispersibility, and large specific surface exhibited significant electrochemical response. This nanohybrid could be directly used for anchoring ESAT-6 binding aptamers (EBA) through the interaction between the 5'-phosphate group (PO

Indexed as

Antigens, BacterialAptamers, NucleotideBacterial ProteinsBiosensing TechniquesCeriumElectrochemical TechniquesHumansLimit of DetectionMetal-Organic FrameworksMycobacterium tuberculosisNanocompositesReproducibility of ResultsZirconiumAntigens, BacterialAptamers, NucleotideBacterial ProteinsCeriumESAT-6 protein, Mycobacterium tuberculosisMetal-Organic FrameworksZirconiumBimetallic organic frameworkCyclic voltammetryElectrochemical aptasensorNitrogen-doped grapheneTuberculosis

Identifiers

PMID34731314
OpenAlexW3209783757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.