ArticleInternational journal of colorectal disease2022
Burden of depression and anxiety among patients with inflammatory bowel disease: results of a nationwide analysis.
Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Association between depression and anxiety with the risk and flare of inflammatory bowel disease: a systematic review and meta-analysis.Internal and emergency medicine · 2025Pooled it
- Predictors of Stress, Anxiety, Depression and Quality of Life in Patients Diagnosed with Chronic Inflammatory Bowel Disease in Romania: A Cross-Section Observational Case-Report Study.Journal of clinical medicine · 2026Article
- Clinical efficacy of Xifeng Huashi and its effect on mental status in patients with diarrheal irritable bowel.World journal of psychiatry · 2026Article
- The SCCAI and Mayo Endoscopic Severity Scores Are Positively Correlated with QIDS-SR16 Depression Scores in Patients with Ulcerative Colitis.Psychology research and behavior management · 2026Article
- Psychological distress differentiates subjective health within a vulnerable subgroup of patients with immune-mediated inflammatory diseases.Frontiers in psychology · 2026Article
- Prevalence of Anxiety and Depression Symptoms Among Patients With Inflammatory Bowel Disease: A Multicenter Study.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Beyond the Plate: Patient Perspectives on Diet and Daily Life with Crohn's Disease-A National Survey.Journal of clinical medicine · 2025Article
- From gut inflammation to psychiatric comorbidity: mechanisms and therapies for anxiety and depression in inflammatory bowel disease.Journal of neuroinflammation · 2025Review
- The Role of Disease Acceptance and Perceived Control in the Subjective Health Experience Model for Immune-Mediated Inflammatory DiseasesBiomedicines · 2025Article
- Screening for Spondyloarthritis in Patients with Inflammatory Bowel Disease - SPARTAN 2024 Annual Meeting Proceedings.Current rheumatology reports · 2025Review
- Early Onset Active Inflammatory Bowel Disease Is Associated With Psychiatric Comorbidities: A Multi-Network Propensity-Matched Cohort Study.Crohn's & colitis 360 · 2025Article
- Moving Towards Acceptance and Values: A Qualitative Study of ACTforIBD Compared to IBD Psychoeducation.Journal of clinical psychology in medical settings · 2024Article
- New insights into the interactions between the gut microbiota and the inflammatory response to ulcerative colitis in a mouse model of dextran sodium sulfate and possible mechanisms of action for treatment with PE&AFWE.Animal models and experimental medicine · 2024Article
- Burden of anxiety and depression among hospitalized patients with irritable bowel syndrome: a nationwide analysis.Irish journal of medical science · 2023Article
- The 2023 Impact of Inflammatory Bowel Disease in Canada: The Influence of Sex and Gender on Canadians Living With Inflammatory Bowel Disease.Journal of the Canadian Association of Gastroenterology · 2023Review
- Depressive and Anxiety Disorders in Patients with Inflammatory Bowel Diseases: Are There Any Gender Differences?International journal of environmental research and public health · 2023Review
- Correlation Analysis Between Disease Activity and Anxiety, Depression, Sleep Disturbance, and Quality of Life in Patients with Inflammatory Bowel Disease.Nature and science of sleep · 2023Article
- Trends in hospital admissions and mortality among inflammatory bowel disease patients with substance use disorder: a 10-year United States nationwide analysis.Proceedings (Baylor University. Medical Center) · 2023Article
- Outcomes of Inflammatory Bowel Disease in Hospitalized Patients With Generalized Anxiety Disorder.Cureus · 2022Article
- Personalising Supportive Healthcare for Immune-Mediated Inflammatory Disorders: A Qualitative Exploration of Patient Needs and Behaviours Based on the Subjective Health Experience Model.International journal of integrated careArticle
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe burden of psychiatric disorders is on a rise in inflammatory bowel disease (IBD) patients which has shown to effect medication compliance and overall clinical outcomes. We studied the prevalence of depression and anxiety in IBD patients when compared to individuals with other chronic medical conditions.
methodsThis is a retrospective cohort study using the United States national inpatient sample of 2016 to 2018. We identified patient encounters with a diagnosis of IBD. Our primary outcome was prevalence of depression and anxiety in IBD patients when compared to general adult population with other chronic medical conditions. We further studied these outcomes in subgroups of patients with ulcerative colitis and Crohn's disease.
resultsA total of 963,619 patient encounters were identified with the diagnosis of IBD between 2016 and 2018, of them 162,850 (16.9%) had depression and 201,685 (20.9%) had anxiety. The prevalence of depression and anxiety was significantly higher in IBD patients in comparison to general population, (16.9% vs 12.3%) and (20.9% vs 15%) respectively (p < 0.001). Association of depression and anxiety was also higher in IBD patients when compared to patients with other chronic conditions like diabetes, metastatic cancer, and coronary artery disease. Crohn's disease and ulcerative colitis were independently associated with increased odds of depression and anxiety and these results were statistically significant (p < 0.001).
conclusionsIBD is associated with increased prevalence of depression and anxiety when compared to general population. Association of these psychiatric illnesses with IBD is significantly higher when compared to other chronic medical conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.