Evidence map›Paper›PMID 34731126›Full record

Observational studyMedicine2021

Detection and characterization of COVID-19 findings in chest CT: Feasibility and applicability of an AI-based software tool.

Andi Gashi, Rahel A Kubik-Huch, Vasiliki Chatzaraki, Anna Potempa, Franziska Rauch, Sasa Grbic, Benedikt Wiggli, Andrée Friedl, Tilo Niemann

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andi GashiDepartment of Health Sciences and Technology, Swiss Federal Institute of Technology, ETH Zurich, 101 Rämistrasse, Zurich, Switzerland.ORCID 0000-0001-9271-549
Rahel A Kubik-HuchDepartment of Radiology, Kantonsspital Baden, 1 Im Ergel, Baden, Switzerland.ORCID 0000-0002-3636-8697
Vasiliki ChatzarakiDepartment of Radiology, Kantonsspital Baden, 1 Im Ergel, Baden, Switzerland.ORCID 0000-0002-9362-4271
Anna PotempaDepartment of Radiology, Kantonsspital Baden, 1 Im Ergel, Baden, Switzerland.ORCID 0000-0003-1258-1490
Franziska RauchSiemens Healthcare GmbH, 3 Siemensstrasse, Forchheim, Germany.
Sasa GrbicSiemens Healthcare GmbH, 3 Siemensstrasse, Forchheim, Germany.ORCID 0000-0002-7564-9811
Benedikt WiggliDepartment of Infectious Diseases, Kantonsspital Baden, 1 Im Ergel, Baden, Switzerland.ORCID 0000-0002-6197-3530
Andrée FriedlDepartment of Infectious Diseases, Kantonsspital Baden, 1 Im Ergel, Baden, Switzerland.ORCID 0000-0003-1405-079
Tilo NiemannDepartment of Radiology, Kantonsspital Baden, 1 Im Ergel, Baden, Switzerland.ORCID 0000-0002-5384-2522

Funding

Guerbet AG no
6 · The paper itself

Abstract

abstractThe COVID-19 pandemic has challenged institutions' diagnostic processes worldwide. The aim of this study was to assess the feasibility of an artificial intelligence (AI)-based software tool that automatically evaluates chest computed tomography for findings of suspected COVID-19.Two groups were retrospectively evaluated for COVID-19-associated ground glass opacities of the lungs (group A: real-time polymerase chain reaction positive COVID patients, n = 108; group B: asymptomatic pre-operative group, n = 88). The performance of an AI-based software assessment tool for detection of COVID-associated abnormalities was compared with human evaluation based on COVID-19 reporting and data system (CO-RADS) scores performed by 3 readers.All evaluated variables of the AI-based assessment showed significant differences between the 2 groups (P < .01). The inter-reader reliability of CO-RADS scoring was 0.87. The CO-RADS scores were substantially higher in group A (mean 4.28) than group B (mean 1.50). The difference between CO-RADS scoring and AI assessment was statistically significant for all variables but showed good correlation with the clinical context of the CO-RADS score. AI allowed to predict COVID positive cases with an accuracy of 0.94.The evaluated AI-based algorithm detects COVID-19-associated findings with high sensitivity and may support radiologic workflows during the pandemic.

Indexed as

AgedAged, 80 and overArtificial IntelligenceCOVID-19COVID-19 Nucleic Acid TestingFeasibility StudiesFemaleHumansLungMaleMiddle AgedPandemicsRetrospective StudiesSARS-CoV-2Tomography, X-Ray Computed

Identifiers

PMID34731126
PMCPMC8519217

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.