Evidence map›Paper›PMID 34731021›Full record

ReviewJournal of clinical microbiology2022

Diagnostic Tests for Detecting Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Specimens.

Paul C Adamson, Jeffrey D Klausner

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Impact of oralmSystems · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Addressing Challenges inMedicina (Kaunas, Lithuania) · 2024
    Review
  7. Review
  8. Review
  9. Visual and rapid identification ofFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Paul C AdamsonDivision of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID 0000-0002-2776-6458
Jeffrey D KlausnerDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-6922-7364
University of California, Los Angeles · USUniversity of Southern California · US

Funding

Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
Evaluating STI screening and antimicrobial resistance in Neisseria gonorrhoeae among PrEP users in VietnamR21AI157817 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KLAUSNER, JEFFREY DAVID, LE, GIANG M · 2021 to 2022
$383k
NIAID NIH HHS R21 AI157817NIMH NIH HHS T32 MH080634
6 · The paper itself

Abstract

Chlamydia trachomatis and Neisseria gonorrhoeae are two of the most often reported bacterial infections in the United States. The rectum and oropharynx are important anatomic sites of infection and can contribute to ongoing transmission. Nucleic acid amplification tests (NAATs) are the mainstays for the detection of C. trachomatis and N. gonorrhoeae infections owing to their high sensitivity and specificity. Several NAATs have been evaluated for testing in rectal and pharyngeal infections. A few assays recently received clearance by the Food and Drug Administration, including one point-of-care test. Those assays can be used for testing in symptomatic individuals, as well as for asymptomatic screening in certain patient populations. Routine screening for C. trachomatis in pharyngeal specimens is not recommended by the Centers for Disease Control and Prevention, though it is often performed due to the use of multiplex assays. While expanding the types of settings for screening and using self-collected rectal and pharyngeal specimens can help to increase access and uptake of testing, additional research is needed to determine the potential benefits and costs associated with increased screening for rectal and pharyngeal C. trachomatis and N. gonorrhoeae infections on a population level.

Indexed as

Chlamydia InfectionsGonorrheaChlamydia trachomatisDiagnostic Tests, RoutineHumansNeisseria gonorrhoeaeNucleic Acid Amplification TechniquesRectumSensitivity and SpecificityChlamydia trachomatisdiagnosticsNeisseria gonorrhoeaenucleic acid technologyoropharyngeal infectionrectal infection

Identifiers

PMID34731021
PMCPMC9020361
OpenAlexW3209955003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.