ArticleActa orthopaedica et traumatologica turcica2021
Comparison of accordion maneuver with compression technique alone for the treatment of atrophic fracture nonunion: A rabbit model.
Article in Acta orthopaedica et traumatologica turcica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- [Effect of accordion technique and deferoxamine on promoting bone regeneration in distraction osteogenesis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to compare the histological results of Accordion Maneuver (AM) with Compression Technique Alone (CA) in the treatment of atrophic fracture nonunion in a rabbit model.
methodsThe study was performed on 91 male New Zealand rabbits aged six months, weighing 3.1 to 3.6 kg. The standardized models of atrophic nonunion with a 3-mm fracture were created in the tibias of rats. For the histomorphological study, 22 rabbits were randomly selected and sacrificed. The remaining 69 rabbits were divided into two groups based on the treatment technique: Group AM (n = 36) and Group CA (n = 33). The group AM was further randomly divided into four subgroups based on the amplitude and interval parameters: subgroup A1B1 (0 day, 4 mm; n = 9), subgroup A1B2 (0 day, 8 mm; n = 7), subgroup A2B1 (6 days, 4 mm; n = 10), and subgroup A2B2 (6 days, 8 mm; n = 10). A monolateral external fixator was employed in each group. Animals were sacrificed 6 weeks after the treatment, and bony healing was assessed both radiologically and histologically. The efficiency of bony healing was assessed using the bone content index, bone mineral density, and bone volume fraction indexes.
resultsIn X-ray and micro-computed tomography assessments, periosteal reaction was detected at the fracture site in all specimens. In group CA, sclerosis was observed at the ends of the fragments. Bony absorption, nonunion, and a little amount of island-like high density were also observed at the nonunion site. Among AM subgroups, sparse callus-like bone formation in A1B1 subgroup and a high density of callus connecting most parts of the gap and large amount of periosteal callus formation in A1B1 subgroup were observed. In A2B2 subgroup, the cortex was initially connected. No gap was observed, and the medullary cavity was recanalized. In histological analyses, the intermission of 0 day at rate of 8 mm was of the highest level of bony regeneration, and the intermission of 6 days at the rate of 4 mm was of the lowest level of bony regeneration (P < 0.05).
conclusionBased on the radiological and histological results obtained from the present study, AM seems to be more effective than CA in treating atrophic nonunion. AM can shorten the period of treatment. The interval of 0 day and an amplitude of 8 mm may be more proper for AM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.