Evidence map›Paper›PMID 34730391›Full record

ArticleJournal of virology2022

Zika Virus Infection in the Ovary Induces a Continuously Elevated Progesterone Level and Compromises Conception in Interferon Alpha/Beta Receptor-Deficient Mice.

Yingying Zhang, Ziyang Sheng, Na Gao, Na Wu, Peigang Wang, Dongying Fan, Deshan Zhou, Gong Cheng, Jing An

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yingying ZhangDepartment of Microbiology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.
Ziyang ShengDepartment of Microbiology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.
Na GaoDepartment of Microbiology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.
Na WuLaboratory Animal Center, Capital Medical Universitygrid.24696.3f, Beijing, China.
Peigang WangDepartment of Microbiology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.
Dongying FanDepartment of Microbiology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.
Deshan ZhouDepartment of Histology and Embryology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.
Gong ChengTsinghua-Peking Center for Life Sciences, School of Medicine, Tsinghua University, Beijing, China.
Jing AnDepartment of Microbiology, School of Basic Medical Sciences, Capital Medical Universitygrid.24696.3f, Beijing, China.ORCID 0000-0002-2567-0380
Capital Medical University · CNCenter for Life Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) belongs to mosquito-borne flaviviruses. Unlike other members in the family, ZIKV can be sexually transmitted, and the female genital tracts are susceptible to ZIKV. However, the impact of ZIKV infection on nonpregnant female reproductive health is not understood. In this study, we investigated the effects of ZIKV infection on the ovary by using nonpregnant female interferon α/β receptor-deficient (

Indexed as

FertilizationAnimalsDisease Models, AnimalEstrous CycleFemaleFollicular AtresiaMiceOvaryProgesteroneReceptor, Interferon alpha-betaSpecies SpecificityVirus ReplicationZika VirusZika Virus InfectionIfnar1 protein, mouseProgesteroneReceptor, Interferon alpha-betaconceptionestrous cyclefemale reproductive healthovaryZika virus

Identifiers

PMID34730391
PMCPMC8791269
OpenAlexW3209521214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.