Evidence map›Paper›PMID 34729963›Full record

SynthesisInvestigative and clinical urology2021

Robotic-assisted versus open simple prostatectomy: Results from a systematic review and meta-analysis of comparative studies.

Simone Scarcella, Daniele Castellani, Vineet Gauhar, Jeremy Yuen-Chun Teoh, Carlo Giulioni, Pietro Piazza, Carlo Andrea Bravi, Ruben De Groote, Geert De Naeyer, Stefano Puliatti and 2 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Investigative and clinical urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Simone Scarcella *Urology Unit, Azienda Ospedaliero-Universitaria "Ospedali Riuniti di Ancona", Università Politecnica delle Marche, Ancona, Italy.ORCID 0000-0003-3015-7271
Daniele Castellani *Urology Unit, Azienda Ospedaliero-Universitaria "Ospedali Riuniti di Ancona", Università Politecnica delle Marche, Ancona, Italy. castellanidaniele@gmail.com.ORCID 0000-0001-7354-9190
Vineet GauharDepartment of Urology, Ng Teng Fong General Hospital, NUHS, Jurong East, Singapore.ORCID 0000-0002-3740-7141
Jeremy Yuen-Chun TeohS.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-9361-2342
Carlo GiulioniUrology Unit, Azienda Ospedaliero-Universitaria "Ospedali Riuniti di Ancona", Università Politecnica delle Marche, Ancona, Italy.ORCID 0000-0001-9934-4011
Pietro PiazzaDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-6740-534X
Carlo Andrea BraviDepartment of Urology, Onze-Lieve-Vrouwziekenhuis, Aalst, Belgium.ORCID 0000-0002-6412-9546
Ruben De GrooteDepartment of Urology, Onze-Lieve-Vrouwziekenhuis, Aalst, Belgium.ORCID 0000-0003-4081-8221
Geert De NaeyerDepartment of Urology, Onze-Lieve-Vrouwziekenhuis, Aalst, Belgium.ORCID 0000-0003-4118-8807
Stefano PuliattiDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-1597-9595
Andrea Benedetto GalosiUrology Unit, Azienda Ospedaliero-Universitaria "Ospedali Riuniti di Ancona", Università Politecnica delle Marche, Ancona, Italy.ORCID 0000-0001-8313-5338
Alexandre MottrieDepartment of Urology, Onze-Lieve-Vrouwziekenhuis, Aalst, Belgium.ORCID 0000-0002-1253-1592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo review safety and efficacy of robotic-assisted simple prostatectomy (RASP) compared to open simple prostatectomy (OP). MATERIALS AND

methodsA comprehensive literature search was performed to assess the differences in perioperative course and functional outcomes in patients with benign prostatic hyperplasia and surgical indication. The incidences of complications were pooled using the Cochran-Mantel-Haenszel Method and expressed as odds ratio (OR), 95% confidence interval (CI), and p-values. Perioperative course and functional outcomes were pooled using the inverse variance of the mean difference (MD), 95% CI, and p-values. Analyses were two-tailed and the significance was set at p<0.05.

resultsEight studies were accepted. Meta-analysis showed significantly longer surgical time (MD, 43.72; 95% CI, 30.57-56.88; p<0.00001) with a significantly lower estimated blood loss (MD, -563.20; 95% CI, -739.95 to -386.46; p<0.00001) and shorter postoperative stay (MD, -2.85; 95% CI, -3.72 to -1.99; p<0.00001) in RASP. Catheterization time did not differ (MD, 0.65; 95% CI, -2.17 to 3.48; p=0.65). The risk of blood transfusion was significantly higher in OP (OR, 0.23; 95% CI, 0.17-0.33; p<0.00001). The risk of recatheterization (OR, 1.96; 95% CI, 0.32-11.93; p=0.47), postoperative urinary infections (OR, 0.89; 95% CI, 0.23-3.51; p=0.87) and 30-day readmission rate (OR, 0.96; 95% CI, 0.61-1.51; p=0.86) did not differ. At 3-month follow-up, functional outcomes were similar.

conclusionsRASP demonstrated a better perioperative outcome and equal early functional outcomes as compared to OP. These findings should be balanced against the longer operative time and higher cost of robotic surgery.

Indexed as

Postoperative ComplicationsProstatectomyRobotic Surgical ProceduresComparative Effectiveness ResearchCost-Benefit AnalysisHumansMaleOperative TimeProstatic HyperplasiaRecovery of FunctionPatient outcome assessmentPostoperative complicationsProstatectomyProstatic hyperplasiaRobotic surgical procedures

Identifiers

PMID34729963
PMCPMC8566792

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.