Evidence map›Paper›PMID 34729786›Full record

ArticleJournal of neurochemistry2022

Lysergic acid diethylamide induces increased signalling entropy in rats' prefrontal cortex.

Aurora Savino, Charles D Nichols

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. The entropic brain today.Brain : a journal of neurology · 2026
    Review
  2. Article
  3. Review
  4. Alternative splicing in addiction.Current opinion in genetics & development · 2025
    Review
  5. Review
  6. Psilocybin desynchronizes brain networks.medRxiv : the preprint server for health sciences · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. The Hallucinogenic SerotoninFrontiers in molecular neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Aurora SavinoDepartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Italy.ORCID 0000-0002-0783-7191
Charles D NicholsLouisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Biotechnology Research Center · IRLouisiana State University Health Sciences Center New Orleans · US

Funding

STEREOCHEMICAL ASPECTS OF HALLUCINOGENESISR01DA002189 · NIDA · PURDUE UNIVERSITY WEST LAFAYETTE · PI NICHOLS, DAVID E · 1985 to 2007
$2.5M
Combining mammalian and Drosophila systems to study neuropsychiatric disordersR01MH083689 · NIMH · LSU HEALTH SCIENCES CENTER · PI NICHOLS, CHARLES D · 2009 to 2012
$1.4M
Stereochemical Aspects of HallucinogenesisR56DA002189 · NIDA · PURDUE UNIVERSITY · PI NICHOLS, DAVID E · 2008 to 2008
$227k
NIDA NIH HHS R01 DA002189NIDA NIH HHS R56 DA002189NIH HHS DA02189NIMH NIH HHS MH083689NIMH NIH HHS R01 MH083689
6 · The paper itself

Abstract

Psychedelic drugs are gaining attention from the scientific community as potential new compounds for the treatment of psychiatric diseases such as mood and substance use disorders. The 5-HT

Indexed as

HallucinogensLysergic Acid DiethylamideAnimalsBrainEntropyPrefrontal CortexRatsHallucinogensLysergic Acid Diethylamide

Identifiers

PMID34729786
PMCPMC9298798
OpenAlexW3210847372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.