Evidence map›Paper›PMID 34729622›Full record

ArticleInternational journal of colorectal disease2022

Adherence to fecal immunochemical test screening among adults at average risk for colorectal cancer.

Deborah A Fisher, Nicole Princic, Lesley-Ann Miller-Wilson, Kathleen Wilson, Kathryn DeYoung, A Burak Ozbay, Paul Limburg

Abstract read
In one paragraph

Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A Multiomic Liquid Biopsy for the Earlier Detection of Colorectal Cancer.Cancer prevention research (Philadelphia, Pa.) · 2026
    Article
  3. Article
  4. Article
  5. From Detection to Delay: Real-World Gaps in Post-CologuardJournal of gastrointestinal cancer · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. A 5-Hydroxymethylcytosine-Based Noninvasive Model for Early Detection of Colorectal Carcinomas and Advanced Adenomas: The METHOD-2 Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Observational
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deborah A FisherDivision of Gastroenterology, Duke University School of Medicine, 3100 Tower Blvd, Durham, NC, 27707, USA.
Nicole PrincicIBM Watson Health, 75 Binney St, Cambridge, MA, 02142, USA. nprincic@us.ibm.com.
Lesley-Ann Miller-WilsonExact Sciences Corporation, 441 Charmany Dr, Madison, WI, 53719, USA.
Kathleen WilsonIBM Watson Health, 75 Binney St, Cambridge, MA, 02142, USA.
Kathryn DeYoungIBM Watson Health, 75 Binney St, Cambridge, MA, 02142, USA.
A Burak OzbayExact Sciences Corporation, 441 Charmany Dr, Madison, WI, 53719, USA.
Paul LimburgDivision of Gastroenterology and Hepatology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study examined adherence to screening for fecal immunochemical test (FIT).

methodsAdults (≥ 50-75) with a FIT between 1/1/2014 and 6/30/2019 in MarketScan administrative claims were selected (index = earliest FIT). Patients were followed for 10 years pre- and 3 years post-index. Patients at increased risk for CRC or with prior screening were excluded. Year over year adherence was measured post-index.

resultsOf 10,253 patients, the proportion adherent to repeat testing at year 2 was 23.4% and 10.6% at year 3. Of 76.6% not adherent in year 2, 5.4% were adherent in year 3.

conclusionResults suggest adherence to FIT tests is poor, minimizing potential benefits. Future studies are needed to consider alternative test options and whether more choice will improve long-term adherence.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerColonoscopyHumansMass ScreeningOccult BloodColorectal neoplasmsGuideline adherenceMass screening

Identifiers

PMID34729622
PMCPMC8885483

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.