Evidence map›Paper›PMID 34729489›Full record

ArticleCritical care explorations2021

A Trigger and Response System for Preventing Cardiac Arrest in the ICU.

Ari Moskowitz, Katherine M Berg, Michael N Cocchi, Anne V Grossestreuer, Mahmoud Issa, Lakshman Balaji, Maureen Chase, Jesse X Yang, Jennifer Sarge, Sharon O'Donoghue and 2 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes.Circulation. Cardiovascular quality and outcomes · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ari MoskowitzCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Katherine M BergCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Michael N CocchiCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Anne V GrossestreuerCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Mahmoud IssaCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Lakshman BalajiCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Maureen ChaseCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Jesse X YangDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA.
Jennifer SargeBeth Israel Deaconess Medical Center, Critical Care Nursing, Boston, MA.
Sharon O'DonoghueBeth Israel Deaconess Medical Center, Critical Care Nursing, Boston, MA.
Todd SargeDivision of Anesthesia Critical Care, Beth Israel Deaconess Medical Center, Boston, MA.
Michael W DonninoCenter for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, MA.
Beth Israel Deaconess Medical Center · USMontefiore Medical Center · US

Funding

Thiamine v placebo to improve oxygen consumption after in-hospital cardiac arrestK23HL128814 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BERG, KATHERINE M · 2016 to 2021
$1.0M
Thiamine as a Renal Protective Agent in Septic ShockK23GM128005 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MOSKOWITZ, ARI · 2018 to 2021
$761k
NHLBI NIH HHS K23 HL128814NIGMS NIH HHS K23 GM128005
6 · The paper itself

Abstract

Although patients in the ICU are closely monitored, some ICU cardiac arrest events may be preventable. In this study, we sought to reduce the rate of cardiac arrests occurring in the ICU through a quality improvement initiative.

designProspective, observational study.

settingICUs of a single tertiary care center. PATIENTS: Patients hospitalized in the ICUs between August 2017 and November 2019.

interventionsA comprehensive trigger and response tool. MEASUREMENT AND MAIN

resultsForty-three patients experienced an ICU cardiac arrest in the preintervention epoch (6.79 arrests per 1,000 discharges), and 59 patients experienced an ICU cardiac arrest in the intervention epoch (7.91 arrests per 1,000 discharges). In the intervention epoch, the clinical trigger and response tool was activated 106 times over a 1-year period, most commonly due to unexpected new/worsening hypotension. There was no step change in arrest rate (2.24 arrests/1,000 patients; 95% CI, -1.82 to 6.28;

conclusionsA novel trigger-and-response tool did not reduce the frequency of ICU cardiac arrest. Additional investigation is needed into the optimal approach for ICU cardiac arrest prevention.

Indexed as

cardiac arrestintensive care unitpreventable harmquality improvement

Identifiers

PMID34729489
PMCPMC8553241
OpenAlexW3205723318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.