Evidence map›Paper›PMID 34729422›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2021

Pott's paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures.

Biniyam A Ayele, Abdinasir Wako, Jarso Tadesse, Hildana Gulelat, Riyad Ibrahim, Sisay Molla, Abdi Bati

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Biniyam A AyeleDepartment of Neurology, Addis Ababa University, Addis Ababa, Ethiopia.
Abdinasir WakoSchool of Medicine, Jijiga University, Jijiga, Ethiopia.
Jarso TadesseSchool of Medicine, Dilla University, Dilla, Ethiopia.
Hildana GulelatYehuleshet Specialty Clinic, Addis Ababa, Ethiopia.
Riyad IbrahimSchool of Medicine, Wolkite University, Wolkite, Ethiopia.
Sisay MollaDepartment of Internal Medicine, Haramaya University, Harar, Ethiopia.
Abdi BatiMedicine and Hepatology and Gastroenterology ALERT Hospital, Addis Ababa, Ethiopia.
Addis Ababa University · ETAll Africa Leprosy Tuberculosis and Rehabilitation Training Centre · ETDilla University · ETHaramaya University · ETJigjiga University · ETWolkite University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) is the leading cause of morbidity and mortality in low and middle income countries (LMIC). Approximately 50% of cases of skeletal TB involve the spine. Failure to identify and treat these areas of involvement at an early stage may lead to serious complications such as vertebral collapse, spinal compression, and spinal deformity. The clinical and radiologic features of Pott's disease may mimic other spine diseases such as, metastatic lesions and other infectious etiologies, this is especially imperative in older patients. CASE REPORT: We report a 60-year-old right handed male patient presented with back pain, paraparesis, and sensory symptoms 2 weeks duration. He has history of dry cough, fatigue, and reduced appetite, but no history of weight loss, fever, night sweat, and bowel/bladder incontinence. No contact history with TB patients. He has a borderline hypertension and diabetes mellitus. Serology for HIV was negative. Thoraco-lumbar magnetic resonance image (MRI) showed destruction of L2 and L3 vertebral body and the inter-vertebral disc; with T2 hyper and T1 hypointensity of the affected vertebral bodies. Probable tuberculous spondylitis with paraparesis was considered and the patient was initiated on antituberculous regimen and short course steroid therapy. After five months treatment, the patient showed significant clinical and radiological improvement.

conclusionIn summary, the present case describes, a patient with Pott's paraplegia due to probable spine tuberculosis and showed significant clinical and radiological improvement following initiation of antituberculous drugs and short course of steroid; indicating the crucial role of imaging in the diagnosis of TB, especially in resource limited settings.

Indexed as

Anti-tuberculous drugsEthiopiaL2, Lumbar level 2L3, Lumbar level 3MRI, magnetic resonance imagePott’s paraplegiaSpinal tuberculosisSSA, sub Saharan AfricaTB, TuberculosisTuberculosis

Identifiers

PMID34729422
PMCPMC8546414
OpenAlexW3208493583

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.