Evidence map›Paper›PMID 34729317›Full record

ArticleActa pharmaceutica Sinica. B2021

TPGS/hyaluronic acid dual-functionalized PLGA nanoparticles delivered through dissolving microneedles for markedly improved chemo-photothermal combined therapy of superficial tumor.

Tingting Peng, Yao Huang, Xiaoqian Feng, Chune Zhu, Shi Yin, Xinyi Wang, Xuequn Bai, Xin Pan, Chuanbin Wu

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

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  10. Recent advances on thermosensitive hydrogels-mediated precision therapy.Asian journal of pharmaceutical sciences · 2024
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  13. [European journal of nuclear medicine and molecular imaging · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Tingting PengCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Yao HuangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xiaoqian FengSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Chune ZhuSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Shi YinSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xinyi WangGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Xuequn BaiSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Chuanbin WuCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Sun Yat-sen University · CNGuangdong Pharmaceutical University · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles (NPs) have shown potential in cancer therapy, while a single administration conferring a satisfactory outcome is still unavailable. To address this issue, the dissolving microneedles (DMNs) were developed to locally deliver functionalized NPs with combined chemotherapy and photothermal therapy (PTT).

Indexed as

ChemotherapyDissolving microneedlesFunctionalized PLGA nanoparticlesHyaluronic acidPhotothermal therapySuperficial tumorTPGS

Identifiers

PMID34729317
PMCPMC8546669
OpenAlexW3109922543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.