ArticleCentral European journal of urology2021
Native tissue repair of cardinal/uterosacral ligaments cures overactive bladder and prolapse, but only in pre-menopausal women.
Article in Central European journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 27 citations in OpenAlex.
- A gynecological perspective of interstitial cystitis/bladder pain syndrome may offer cure in selected cases.Central European journal of urology · 2022Trial
- Comparison of Postoperative Functional Recovery and Anatomical Restoration in Patients with Pelvic Organ Prolapse Undergoing Three Types of Apical Suspension Techniques: A Retrospective Study.International urogynecology journal · 2026Article
- Bilateral Sacrospinous Colposuspension with Sling for Advanced Pelvic Organ Prolapse: Anatomical and Functional Outcomes in a 235-Patient Cohort.Journal of clinical medicine · 2026Article
- 3D MRI Biomarkers for Predicting Pelvic Organ Prolapse Risk and Severity.International urogynecology journal · 2026Article
- A Critical Examination of Ligamentous Pathogenesis of Bladder Pain/Lower Urinary Tract Symptoms Using the UEDA Criteria.International neurourology journal · 2024Article
- Chronic pelvic pain of "unknown origin" in the female.Annals of translational medicine · 2024Review
- A comparison of native vaginal and ligament surgery for cure of pelvic organ prolapse and overactive bladder.Annals of translational medicine · 2024Review
- A practical ligament-based diagnostic system for cure of pelvic symptoms and prolapse.Annals of translational medicine · 2024Review
- Simulated operations (SOs) apply mechanical support to structures to confirm symptom causation.Annals of translational medicine · 2024Review
- Wide-bore polyester sutures may create sufficient collagen for cure of prolapse/incontinence: a work in progress.Annals of translational medicine · 2024Review
- Tension-free artisan tape: a low-cost option for cure of pelvic organ prolapse and stress incontinence.Annals of translational medicine · 2024Review
- Structural, functional, and dysfunctional pelvic anatomy.Annals of translational medicine · 2024Review
- A brief physiology and pathophysiology of the bladder.Annals of translational medicine · 2024Review
- Principles of surgery according to the Integral Theory Paradigm (ITP).Annals of translational medicine · 2024Review
- Lax Uterosacral Ligament and Urge Urinary Incontinence: MRI Findings in Symptomatic Patients Versus Healthy Volunteers.International urogynecology journal · 2024Article
- Defining urge as an uncontrolled micturition explains pathogenesis, informs cure and helps solve the burgeoning OAB crisis.Neurourology and urodynamics · 2022Review
- THE CASE AGAINST urethral failure is not a critical factor in female urinary incontinence. Now what? The integral theory system.Neurourology and urodynamics · 2022Article
- The emperor has no clothes: OAB can be cured surgically.International urogynecology journal · 2022Article
- An anatomical pathogenesis of lower urinary tract definitions from the 2002 ICS report symptoms, conditions, syndromes, urodynamics.Neurourology and urodynamics · 2022Review
- Comparing urethral closure mechanisms.Central European journal of urology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this article was to study the effect of native tissue cardinal/uterosacral ligament repair on overactive bladder (OAB) and pelvic organ prolapse (POP). MATERIAL AND
methodsInclusion criteria included decrease of urge symptoms following insertion of a gauze tampon in the posterior fornix of vagina ('simulated operation'). Exclusion criteria included SUI, POP grades 3-4. The surgery consisted of plication of cardinal/uterosacral ligaments. Post-operative assessment was performed at3, 6, 12 and 18 months after surgery and included evaluation by stage of prolapse, Urinary Distress Inventory Short Form 6 (UDI-6), Overactive Bladder Questionnaire (OAB-q), Pelvic Floor Impact Questionnaire- Short Form 7 (PFIQ-7), and International Consultation on Incontinence Questionnaire - Urinary Incontinence Short Form (ICIQ-SF) questionnaires and voiding diary.
resultsAt 3 months, cure rates for frequency, urgency, nocturia and prolapse were comparable. By the 6-month review, catastrophic failure commenced in the postmenopausal group, parallel for all pa-rameters, starkly contrasting with premenopausal group. At 18 months, % cure rates for pre-menopausal (post-menopausal in brackets) were 79.6 (15.4) for POP, 67.3 (20.5) for urgency, 87.7 (20.5) for nocturia and 59.2 (15.4) for frequency.
conclusionsWe hypothesize the stepwise parallel recurrence of POP and symptoms in the menopausal group was a consequence of collagen deficiency in the plicated ligaments. Nevertheless, plication of uterosacral-cardinal ligament complex is simple, inexpensive, effective, especially applicable pre-menopausally for POP and as an alternative treatment option in that difficult group of pre-menopausal women who have major OAB/nocturia symptoms but only minimal prolapse.
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