Evidence map›Paper›PMID 34729082›Full record

ArticleEFSA journal. European Food Safety Authority2021

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed.
Part 2:

EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez-Ordóñez, Declan Bolton, Sara Bover-Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare and 28 more

Open access · diamondAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 1 institution in 1 country.

EFSA Panel on Biological Hazards (BIOHAZ)
Ana Allende
Konstantinos Koutsoumanis
Ana Allende
Avelino Alvarez-Ordóñez
Declan Bolton
Sara Bover-Cid
Marianne Chemaly
Robert Davies
Alessandra De Cesare
Lieve Herman
Friederike Hilbert
Roland Lindqvist
Maarten Nauta
Giuseppe Ru
Marion Simmons
Panagiotis Skandamis
Elisabetta Suffredini
Dan I Andersson
Vasileios Bampidis
Johan Bengtsson-Palme
Damien Bouchard
Aude Ferran
Maryline Kouba
Secundino López Puente
Marta López-Alonso
Søren Saxmose Nielsen
Alena Pechová
Mariana Petkova
Sebastien Girault
Alessandro Broglia
Beatriz Guerra
Matteo Lorenzo Innocenti
Ernesto Liébana
Gloria López-Gálvez
Paola Manini
Pietro Stella
Luisa Peixe
Animal Welfare Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specific concentrations of apramycin, paromomycin, neomycin and spectinomycin in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield, were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC for these antimicrobials, it was not possible to conclude the assessment until further experimental data become available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels in feed that showed to have an effect on growth promotion/increased yield were reported for apramycin and neomycin, whilst for paromomycin and spectinomycin, no suitable data for the assessment were available. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these four antimicrobials.

Indexed as

antimicrobial resistanceapramycinfood‐producing animalsgrowth promotionneomycinparomomycinspectinomycin

Identifiers

PMID34729082
PMCPMC8546520
OpenAlexW3210642243

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.