ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2021
The prevalence and possible causes of enteral tube feeding intolerance in critically ill patients: A cross-sectional study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Effects of continuous versus intermittent enteral feeding on feeding tolerance in critically ill adults: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Systematic evaluation of risk prediction models for feeding intolerance in ICU patients during enteral nutrition.Asia Pacific journal of clinical nutrition · 2025Pooled it
- Risk factors for enteral feeding intolerance in critically ill patients: an updated systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Strategies to Maximize the Benefits of Evidence-Based Enteral Nutrition: A Narrative Review.Nutrients · 2025Pooled it
- Risk prediction models for feeding intolerance in patients with enteral nutrition: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Impact of a Staged Enteral Nutrition Nursing Pathway Based on Dynamic Assessment of Tolerance and Aspiration Risk vs Usual Care on Feeding Intolerance in Older Adult Patients With Acute Ischemic Stroke and Dysphagia: A Single-Center Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026Trial
- Accuracy of Bedside Methods for Preliminary Nasoenteric Tube Tip Localization in Intensive Care: A Prospective Diagnostic Study.Nursing in critical care · 2026Article
- Risk stratification of postoperative enteral feeding intolerance using explainable machine learning in oral cancer free flap reconstruction.Frontiers in nutrition · 2026Article
- The Japanese Critical Care Nutrition Guideline 2024.Journal of intensive care · 2025Review
- Construction and evaluation of a machine learning-based predictive model for enteral nutrition feeding intolerance risk in ICU patients.Frontiers in nutrition · 2025Article
- Clinical practice guidelines for nutritional assessment and monitoring of adult ICU patients in China.Journal of intensive medicine · 2024Article
- Different definitions of feeding intolerance and their associations with outcomes of critically ill adults receiving enteral nutrition: a systematic review and meta-analysis.Journal of intensive care · 2023Review
- Related Factor Analysis and Nursing Strategies of Diarrhea in Critically Ill Patients with Enteral Nutrition.Emergency medicine international · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnteral tube feeding intolerance (ETFI) is one of the most common complications of enteral nutrition (EN), which may lead to increased mortality and length of intensive care unit (ICU) stay. This study aimed to determine the prevalence of ETFI and effects on feeding intolerance on nutrition and clinical outcomes in Iran. MATERIALS AND
methodsThis cross-sectional study was conducted in 2019 at the three general ICUs of Imam Reza Hospital in Mashhad, Iran, during 7 days on 245 patients. The collected data included demographic characteristics, primary diagnosis, the Acute Physiology and Chronic Health Evaluation II (APACHE ІІ) score, Sequential Organ Failure Assessment (SOFA) score, duration of mechanical ventilation, and length of ICU stay. Feeding intolerance was assessed using daily questionnaires for 7 days. ETFI was determined as the interruption of EN based on gastrointestinal causes, including large gastric residuals, abdominal distension, vomiting, diarrhea, and subjective discomfort.
resultsOverall, 245 critically ill patients (122 males and 123 females) were included in this study, with a mean age of 58.43 ± 19.2 years in three general ICUs. The highest prevalence rate of ETFI was 91.8%, which occurred on the 2
conclusionETFI was prevalent in almost two-third (66%) of the critically ill patients receiving EN based on the GRV. ETFI was associated with deteriorated nutritional status and clinical outcomes.
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