Evidence map›Paper›PMID 34728952›Full record

ArticleAnnals of Indian Academy of Neurology

Neurosyphilis, A True Chameleon of Neurology.

Shripad S Pujari, Rahul V Kulkarni, Dhananjay Duberkar, Satish Nirhale, Dattatraya Nadgir, Pramod Dhonde, Tejas Sakale, Prafulla Shembalkar, Chandrashekhar Meshram

Open access · diamondAbstract read
In one paragraph

Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shripad S PujariNeurology Department, Deenanath Mangeshkar Hospital and Research Centre, Pune, Maharashtra, India.
Rahul V KulkarniNeurology Department, Deenanath Mangeshkar Hospital and Research Centre, Pune, Maharashtra, India.
Dhananjay DuberkarNeurology Department, Sahyadri Hospital, Nashik, Maharashtra, India.
Satish NirhaleDepartment of Neurology, D. Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India.
Dattatraya NadgirNeurology Department, Brain and Nerve Clinic, Neurology and Neuro- Opthalmology, Hubli, Karnataka, India.
Pramod DhondeNeurology Department, Dhonde Hospital, Nanded, Maharashtra, India.
Tejas SakaleNeurology Department, Ashoka Medicover Hospital, Nashik, Maharashtra, India.
Prafulla ShembalkarNeurology Department, Getwell Hospital and Research Institute, Nagpur, Maharashtra, India.
Chandrashekhar MeshramNeurology Department, Brain and Mind Institute, Nagpur, Maharashtra, India.
Dr. D. Y. Patil Medical College, Hospital and Research Centre · INInstitute of Mind Control & Brain Development · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurosyphilis (NS) is a rarely encountered scenario today. Manifestations are heterogeneous, and their characteristics have changed in the antibiotic era. A differential diagnosis of NS is not commonly thought of even with relevant clinical-radiological features, as it mimics many common neurological syndromes.

objectivesTo study the manifestations of NS in the present era and the process of diagnosis.

methodThe data of ten patients with NS was collected and analyzed. Their background data, clinical features, investigations, the process of reaching the diagnosis, management and outcomes were recorded. OBSERVATIONS AND

resultsThe manifestations of NS in our cohort included six patients with cognitive decline/encephalopathy and one each with meningitis with cranial nerve palsies, cerebellar ataxia, myelitis and asymptomatic NS. The presence of Argyll Robertson pupil helped to clinch diagnosis in one patient. Treponemal tests were ordered in two patients only after alternative etiologies were looked at, to begin with, whereas in six patients treponemal test was requested as a part of standard workup for dementia/ataxia.

conclusionsNS dementia and behavior changes are mistaken for degenerative, vascular, nutritional causes, autoimmune encephalitis or prion disease. Meningitis has similarities with infective (tubercular), granulomatous (sarcoidosis, Wegener's), collagen vascular disease and neoplastic meningitis, and myelitis simulates demyelination or nutritional myelopathy (B

Indexed as

Asymptomatic neurosyphiliscerebellar ataxiadementiameningitismyelitis

Identifiers

PMID34728952
PMCPMC8513946
OpenAlexW3176417560

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.