Evidence map›Paper›PMID 34728919›Full record

ArticleJournal of Indian Association of Pediatric Surgeons

Clinicopathological Study of Primary Pediatric Gastrointestinal Lymphomas.

Moupali Ghosh, Moumita Sengupta, Shibsankar Barman, Uttara Chatterjee, Madhumita Mukhopadhyay, Ruchirendu Sarkar, Koushik Saha, Ashoke Kumar Basu

Open access · diamondAbstract read
In one paragraph

Article in Journal of Indian Association of Pediatric Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Moupali GhoshDepartment of Pathology, IPGME&R, Kolkata, West Bengal, India.
Moumita SenguptaDepartment of Pathology, IPGME&R, Kolkata, West Bengal, India.
Shibsankar BarmanDepartment of Pediatric Surgery, IPGME&R, Kolkata, West Bengal, India.
Uttara ChatterjeeDepartment of Pathology, IPGME&R, Kolkata, West Bengal, India.
Madhumita MukhopadhyayDepartment of Pathology, IPGME&R, Kolkata, West Bengal, India.
Ruchirendu SarkarDepartment of Pediatric Surgery, IPGME&R, Kolkata, West Bengal, India.
Koushik SahaDepartment of Pediatric Surgery, NRS Medical College, Kolkata, West Bengal, India.
Ashoke Kumar BasuDepartment of Pediatric Surgery, Institute of Child Health, Kolkata, West Bengal, India.
Institute of Post Graduate Medical Education and Research · INMedical College and Hospital, Kolkata · INInstitute of Child Health · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary gastrointestinal lymphomas (PGIL) are uncommon in children and account for <5% of all pediatric malignancies. The objective of our study was to analyze the prognostic factors of pediatric PGILs with reference to its histological subtypes, stage, and outcomes using immunohistochemistry. MATERIALS AND

methodsTwenty cases were studied over 11 years. Clinicopathological profiles, histological details, and immunohistochemical (IHC) profiles were analyzed.

resultsThe mean age at the presentation was 6 years. Using IHC stains (CD CD10, CD19, CD20, CD3, terminal deoxynucleotidyl transferase, BCL 2 and 6, PAX 5, and MUM1), diffuse large B-cell lymphoma (DLBCL) was most prevalent (45%), followed by Burkitt lymphoma (35%) and lymphoblastic lymphoma (20%). DLBCLs (9) were classified using the Han's algorithm. Six were activated B-cell and 3 were germinal center B-cell subtypes. The cases of lymphoblastic lymphoma and those in Stage I disease had the best prognosis.

conclusionPediatric PGILs have variable presentation, outcomes, and diverse treatment modalities depending on the histological subtypes. A panel of IHC stains can be a useful adjunct for the categorization and prognosis of pediatric PGILs.

Indexed as

Burkitt lymphomadiffuse large B-cell lymphomalymphoblastic lymphomapediatric gastrointestinal lymphomas

Identifiers

PMID34728919
PMCPMC8515530
OpenAlexW3199734393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.