Evidence map›Paper›PMID 34728860›Full record

ArticleNature2021

Gut microbes regroup to aid defence after infection.

Melissa M Kendall, Vanessa Sperandio

Abstract readComment
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Role of the Microbiome in the Pathogenesis of COVID-19.Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Melissa M KendallDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.
Vanessa SperandioDepartments of Microbiology and Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Funding

Quorum Sensing Regulation of EHEC Virulence GenesR37AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VANESSA SPERANDIO · 2018 to 2026
$5.3M
Sugar regulation of EHEC virulenceR01AI154597 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MARESSO, ANTHONY W, SPERANDIO, VANESSA · 2020 to 2024
$3.1M
Tryptophan derivatives in EHEC pathogenesisR01AI155398 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2021 to 2025
$3.0M
NIAID NIH HHS R01 AI154597NIAID NIH HHS R01 AI155398NIAID NIH HHS R37 AI053067
6 · The paper itself

Abstract

Resident gut microbes can help to block infection, but the mechanisms involved are not fully understood. It has now been found that changes in the microbial community after infection boost the level of a molecule that combats harmful bacteria.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaBacteria

Identifiers

PMID34728860
PMCPMC8162939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.