Pharmacokinetics and bioavailability of ketoprofen when compounded with iron dextran for use in nursing piglets.

Kristen J Reynolds, Ron Johnson, Robert M Friendship, Jennifer Brown, Saad Enouri, Ronette Gehring, Terri L O'Sullivan

Open access · greenAbstract read

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.5field-weighted citation impact, top 35% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

Ketoprofen as an emerging contaminant: occurrence, ecotoxicity and (bio)removal.Frontiers in microbiology · 2023
Review
Pharmacokinetics of combined administration of iron dextran with meloxicam or flunixin meglumine in piglets.The Canadian veterinary journal = La revue veterinaire canadienne · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kristen J ReynoldsDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

Ron JohnsonDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

Robert M FriendshipDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

Jennifer BrownDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

Saad EnouriDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

Ronette GehringDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

Terri L O'SullivanDepartment of Population Medicine (Reynolds, Friendship, O'Sullivan), Department of Biomedical Sciences (Johnson, Enouri), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada; Prairie Swine Center, Saskatoon, Saskatchewan (Brown); College of Veterinary Medicine, Kansas State University, USA; Universiteit Utrecht, The Netherlands (Gehring).

University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Canada, piglets receive analgesia to control pain after surgical castration. There is interest in examining the potential to mix non-steroidal anti-inflammatory drugs with iron dextran prior to injection to minimize piglet handling and labor. The objective of this study was to compare pharmacokinetics and the relative bioavailability of ketoprofen given alone (3.0 mg/kg IM)

Indexed as

KetoprofenAnimalsAnti-Inflammatory Agents, Non-SteroidalBiological AvailabilityDextransIronSwineAnti-Inflammatory Agents, Non-SteroidalDextransIronKetoprofen

Identifiers

PMID34728849

PMCPMC8543655

OpenAlexW3208527874

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.