Observational studyScientific reports2021
Association of changes in lipid levels with changes in vitamin D levels in a real-world setting.
Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Vitamin D Status, Cardiovascular Risk Profile, and miRNA-21 Levels in Hypertensive Patients: Results of the HYPODD Study.Nutrients · 2022Trial
- Association between serum vitamin D levels and atherogenic lipid subfractions: insights from NMR-based lipid profiling in a large adult population.Scientific reports · 2026Article
- [Optimal serum 25(OH)D levels in relation to musculoskeletal, metabolic, neurological, autoimmune and infectious diseases].Problemy endokrinologii · 2026Review
- Correlation between 25-hydroxyvitamin D levels and remnant cholesterol in patients with type 2 diabetes.BMC endocrine disorders · 2025Article
- Vitamin D and Chronic Disorders: A Review of Metabolic and Cardiovascular Diseases.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Multiple facets of HDLs as modifiable risk factors in stroke-the good, the bad, and the ugly.Journal of lipid research · 2025Review
- Review
- The diagnostic value of the combined application of blood lipid metabolism markers and interleukin-6 in osteoporosis and osteopenia.Lipids in health and disease · 2025Article
- Effects of dietary supplementation with vitamin A, DVeterinary and animal science · 2024Article
- Alterations in serum levels of calcium, vitamin D, phosphorus, and parathyroid hormone in patients with clinically confirmed familial hypercholesterolemia: a cross-sectional study.Annals of medicine and surgery (2012) · 2024Article
- Association between vitamin D deficiency and serum lipid levels in a group of Romanian patients.Medicine and pharmacy reports · 2024Article
- Targeted metabolomics profiling in pregnancy associated with vitamin D deficiency.BMC pregnancy and childbirth · 2024Article
- Review
- Vitamin D Deficiency in Patients Hospitalized for Heart Failure Living in the Tropics.International journal of heart failure · 2024Article
- Vitamin D and cardiovascular diseases: A narrative review.Journal of family medicine and primary care · 2024Review
- Correlation between bone density, bone metabolism markers with lipid metabolism markers and body mass index.BMC musculoskeletal disorders · 2024Article
- Nonlinear relationship between serum 25-hydroxyvitamin D and lipid profile in Chinese adults.Frontiers in nutrition · 2024Article
- The causal relationship between 25-hydroxyvitamin D and serum lipids levels: A bidirectional two-sample mendelian randomization study.PloS one · 2024Article
- Can the supplementation of vitamin D, sun exposure, and isolation during the COVID-19 pandemic affect the seasonal concentration of 25(OH)D and selected blood parameters among young soccer players in a one-year training season?Journal of the International Society of Sports Nutrition · 2023Article
- Using Machine Learning to Identify the Relationships between Demographic, Biochemical, and Lifestyle Parameters and Plasma Vitamin D Concentration in Healthy Premenopausal Chinese Women.Life (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In clinical trials, vitamin D supplementation has been reported to reduce serum levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) but not high-density lipoprotein cholesterol (HDL-C). In this cohort study we evaluated the association between changes in vitamin D (25-hydroxyvitamin D) and changes in lipid levels in a real-world setting. Changes in lipid levels over a 1-year period were evaluated among individuals whose vitamin D levels increased (group 1) or decreased (group 2) by ≥ 10 ng/mL in year 2018 versus 2017 (cohort 1; n = 5580), in 2019 versus 2018 (cohort 2, n = 6057), or in 2020 versus 2019 (cohort 3, n = 7249). In each cohort, levels of TC, LDL-C, and TG decreased in group 1 and increased in group 2. Between-group differences in average changes in the 3 cohorts ranged from 10.71 to 12.02 mg/dL for TC, from 7.42 to 8.95 mg/dL for LDL-C, and from 21.59 to 28.09 mg/dL for TG. These differences were significant after adjusting for age, sex, race, education, body mass index, blood pressure, smoking status, geographical location, and baseline levels of vitamin D and lipids (P < 0.001). Changes in vitamin D levels were not significantly associated with changes in HDL-C levels.
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