Evidence map›Paper›PMID 34728772›Full record

ArticleCommunications biology2021

CD36 maintains the gastric mucosa and associates with gastric disease.

Miriam Jacome-Sosa, Zhi-Feng Miao, Vivek S Peche, Edward F Morris, Ramkumar Narendran, Kathryn M Pietka, Dmitri Samovski, Hei-Yong G Lo, Terri Pietka, Andrea Varro and 6 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Recent advances in carotenoid absorption, distribution, and elimination.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2025
    Review
  5. Infection and immunity · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Vascular and lymphatic regulation of gastrointestinal function and disease risk.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Review
  13. Cell plasticity in regeneration in the stomach and beyond.Current opinion in genetics & development · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Miriam Jacome-SosaCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. mjacome@wustl.edu.ORCID 0000-0003-3949-3618
Zhi-Feng MiaoDepartment of Surgical Oncology, Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, First Hospital of China Medical University, Shenyang, China.
Vivek S PecheCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Edward F MorrisCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Ramkumar NarendranCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Kathryn M PietkaCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Dmitri SamovskiCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Hei-Yong G LoDivision of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-7253-6873
Terri PietkaCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Andrea VarroInstitute of Translational Medicine, University of Liverpool, Liverpool, UK.
Latisha Love-GregoryDepartment of Pathology & Immunology, Washington University School of Medicine, St Louis, MO, USA.
James R GoldenringDepartments of Surgery and Cell and Developmental Biology, Vanderbilt University Medical Center and VA Medical Center, Nashville, TN, USA.ORCID 0000-0002-7833-2940
Ondrej KudaInstitute of Physiology, Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic.ORCID 0000-0001-7034-4536
Eric R GamazonDivision of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-4204-8734
Jason C MillsGastroenterology & Hepatology Section, Departments of Medicine and of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. Jason.Mills@bcm.edu.
Nada A AbumradCenter for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. nabumrad@wustl.edu.ORCID 0000-0002-6475-0877
Washington University in St. Louis · USBaylor College of Medicine · USCzech Academy of Sciences · CZUniversity of Cambridge · GBUniversity of Liverpool · GBVanderbilt University Medical Center · US

Funding

Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
SMALL GTP BINDING PROTEINS IN GASTROINTESTINAL MUCOSAR01DK048370 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOLDENRING, JAMES RICHARD · 1994 to 2025
$10.1M
CD36 AND INTESTINAL FAT ABSORPTIONR01DK060022 · NIDDK · WASHINGTON UNIVERSITY · PI ABUMRAD, NADA A. · 2001 to 2021
$7.7M
REGULATION OF ATROPHY-INDUCED PROGENITOR CELLS IN THE GASTRIC CORPUSR01DK094989 · NIDDK · WASHINGTON UNIVERSITY · PI Jason C Mills · 2012 to 2026
$6.1M
Induction and Evolution of Metaplasia in the StomachR01DK101332 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eunyoung Choi, James Richard Goldenring · 2014 to 2026
$5.9M
MECHANISMS OF CHIEF CELL DEDIFFERENTIATIONR01DK105129 · NIDDK · WASHINGTON UNIVERSITY · PI Jason C Mills · 2015 to 2026
$5.4M
Haplotype-aware models of gene and isoform expression with application to genetic studies of disease in diverse populationsR01GM140287 · NIGMS · SEATTLE CHILDREN'S HOSPITAL · PI GAMAZON, ERIC R, MOHAMMADI, PEJMAN · 2021 to 2024
$2.8M
Functional Genomics: A Phenome-wide SurveyR35HG010718 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GAMAZON, ERIC R · 2019 to 2023
$2.2M
Mechanisms Governing Expansion of Embryonic Progenitor Cells (EPCs) inMetaplasiaR01CA239645 · NCI · WASHINGTON UNIVERSITY · PI MILLS, JASON C · 2020 to 2024
$2.1M
Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NCI NIH HHS R01 CA239645NCI NIH HHS R01 CA246208NCRR NIH HHS S10 RR027552NHGRI NIH HHS R01 HG011138NHGRI NIH HHS R35 HG010718NIA NIH HHS R56 AG068026NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK052574NIDDK NIH HHS P30 DK056338NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK048370NIDDK NIH HHS R01 DK060022NIDDK NIH HHS R01 DK094989NIDDK NIH HHS R01 DK101332NIDDK NIH HHS R01 DK105129NIDDK NIH HHS R01 DK111175NIGMS NIH HHS R01 GM140287
6 · The paper itself

Abstract

The gastric epithelium is often exposed to injurious elements and failure of appropriate healing predisposes to ulcers, hemorrhage, and ultimately cancer. We examined the gastric function of CD36, a protein linked to disease and homeostasis. We used the tamoxifen model of gastric injury in mice null for Cd36 (Cd36

Indexed as

AnimalsCD36 AntigensEndothelial CellsFemaleGastric MucosaGastritisGastrointestinal HemorrhageMaleMiceMice, Inbred C57BLStomach UlcerCD36 AntigensCd36 protein, mouse

Identifiers

PMID34728772
PMCPMC8563937
OpenAlexW3208673819

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.