Evidence map›Paper›PMID 34728728›Full record

ArticleScientific reports2021

Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K

Benjamin A Heitz, Robert Bränström, Wei Yang, Yiding Huang, Tilo Moede, Ingo B Leibiger, Barbara Leibiger, Liu Qi Chen, Jia Yu, Shao-Nian Yang and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Benjamin A Heitz *Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Robert Bränström *The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden. robert.branstrom@ki.se.
Wei YangDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Yiding HuangDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Tilo MoedeThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Ingo B LeibigerThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Barbara LeibigerThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Liu Qi ChenDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Jia YuThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Shao-Nian YangThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Olof LarssonThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
S Scott SaavedraDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Per-Olof BerggrenThe Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Craig A AspinwallDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
University of Arizona · USKarolinska Institutet · SEKarolinska University Hospital · SE

Funding

Sniffer Biosensors Based on Ion Channel-GPCR Chimeras and Polylipid MembranesR01EB007047 · NIBIB · UNIVERSITY OF ARIZONA · PI ASPINWALL, CRAIG A, SAAVEDRA, STEVEN SCOTT · 2006 to 2015
$3.5M
Bio/Chemical Mapping of Pancreatic Cell ActivityR21EB022297 · NIBIB · TRUSTEES OF INDIANA UNIVERSITY · PI BAKER, LANE A. · 2016 to 2017
$407k
Understanding genetics of aging: Canis familiaris modelF32AG022297 · NIA · TEXAS A&M UNIVERSITY SYSTEM · PI GREER, KIMBERLY A · 2003 to 2004
$83k
European Research Council ERC-2018-AdG 834860 EYELETSNational Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health EB007047National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health EB022297National Science Foundation 0548167NIBIB NIH HHS R01 EB007047NIBIB NIH HHS R21 EB022297
6 · The paper itself

Abstract

ATP-sensitive K

Indexed as

Adenosine DiphosphateAdenosine TriphosphateAnimalsCell MembraneHEK293 CellsHumansIon Channel GatingKcnj11 ChannelOocytesPotassium Channels, Inwardly RectifyingSulfonylurea ReceptorsXenopus laevisAdenosine DiphosphateAdenosine TriphosphateKcnj11 ChannelPotassium Channels, Inwardly RectifyingSulfonylurea Receptors

Identifiers

PMID34728728
PMCPMC8564548
OpenAlexW3209449154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.