Evidence map›Paper›PMID 34728647›Full record

ArticleScientific reports2021

Antimicrobial and cytotoxic capacity of pyroligneous extracts films of Eucalyptus grandis and chitosan for oral applications.

Juliana Leitzke Santos de Souza, Tomaz Alves, Laísa Camerini, Fernanda Nedel, Angela Diniz Campos, Rafael Guerra Lund

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Plants (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Microorganisms · 2025
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Juliana Leitzke Santos de SouzaPost-Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas, Eliseu Maciel Avenue, Building 31, Pelotas, RS, 96010-900, Brazil.ORCID http://orcid.org/0000-0002-1363-4083
Tomaz AlvesGraduate Program in Oral and Craniofacial Biomedicine, University of North Carolina at Chapel Hill, 385 S Columbia St, Chapel Hill, NC, 27599, USA.ORCID http://orcid.org/0000-0002-3377-725X
Laísa CameriniPost-Graduate Program in Health and Behavior, Catholic University of Pelotas, 373 Gonçalves Chaves Street, Room 411C, Pelotas, RS, 96015-560, Brazil.ORCID http://orcid.org/0000-0002-4811-7887
Fernanda NedelPost-Graduate Program in Health and Behavior, Catholic University of Pelotas, 373 Gonçalves Chaves Street, Room 411C, Pelotas, RS, 96015-560, Brazil.ORCID http://orcid.org/0000-0002-9055-8328
Angela Diniz CamposBrazilian Agricultural Research Corporation, Embrapa Temperate Climate, Highway BR-392, 78th km, 9th district, Monte Bonito, Pelotas, RS, 96010-971, Brazil.ORCID http://orcid.org/0000-0002-5234-3035
Rafael Guerra LundPost-Graduate Program in Biochemistry and Bioprospecting, Laboratory of Oral Microbiology, Pelotas Dental School, Federal University of Pelotas, 457 Gonçalves Chaves, Room 503, Pelotas, RS, 96015-560, Brazil. rafael.lund@gmail.com.ORCID http://orcid.org/0000-0003-1006-3809
Universidade Católica de Pelotas · BRUniversidade Federal de Pelotas · BRBrazilian Agricultural Research Corporation · BRUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan films containing distilled pyroligneous extracts of Eucalyptus grandis (DPEC), characterized and developed by Brazilian Agricultural Research Corporation-Embrapa Temperate Agriculture (EMBRAPA-CPACT), were evaluated for antimicrobial activity against Candida albicans, Streptococcus mutans, and Lactobacillus acidophilus by direct contact test. Further, their capacity for the prevention of teeth enamel demineralization and cytotoxicity in vitro were also determined. The natural polymers were tested at different concentrations (1500-7500 µg mL

Indexed as

Administration, OralAdultAnimalsAnti-Bacterial AgentsBacteriaBiofilmsCariostatic AgentsCell ProliferationChitosanEucalyptusFemaleHumansMiceNIH 3T3 CellsPlant ExtractsPolymersAnti-Bacterial AgentsCariostatic AgentsChitosanPlant ExtractsPolymerspyroligneous acidTerpenes

Identifiers

PMID34728647
PMCPMC8563853
OpenAlexW3208451713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.