Evidence map›Paper›PMID 34728603›Full record

ArticleSpinal cord series and cases2021

An investigation to the prolonged requirement (>7 days) of vasopressors in cervical spinal cord injury patients-a retrospective analysis.

Rajeeb Kumar Mishra, Keshav Goyal, Ashish Bindra, Gyaninder Pal Singh, Niraj Kumar, Navdeep Sokhal, Kapil Dev Soni, Shweta Kedia, Sagar Dev Barman

Open access · bronzeAbstract read
In one paragraph

Article in Spinal cord series and cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rajeeb Kumar MishraDepartment of Neuroanaesthesia and neurocritical care, National Institute of Mental Health and Neurosciences, Bengaluru, 560029, India.
Keshav GoyalDepartment of Neuroanaesthesia and critical care, All India Institute of Medical Sciences, New Delhi, 110029, India. Keshavgoyalster@gmail.com.ORCID 0000-0001-9139-0689
Ashish BindraDepartment of Neuroanaesthesia and critical care, All India Institute of Medical Sciences, New Delhi, 110029, India.
Gyaninder Pal SinghDepartment of Neuroanaesthesia and critical care, All India Institute of Medical Sciences, New Delhi, 110029, India.
Niraj KumarDepartment of Neuroanaesthesia and critical care, All India Institute of Medical Sciences, New Delhi, 110029, India.
Navdeep SokhalDepartment of Neuroanaesthesia and critical care, All India Institute of Medical Sciences, New Delhi, 110029, India.
Kapil Dev SoniDepartment of Critical and Intensive Care, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, 110029, India.
Shweta KediaDepartment of Neurosurgery, Neurosciences centre, All India Institute of Medical Sciences, New Delhi, 110029, India.
Sagar Dev BarmanDepartment of Neuroanaesthesia and critical care, All India Institute of Medical Sciences, New Delhi, 110029, India.
All India Institute of Medical Sciences · INNational Institute of Mental Health and Neurosciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective chart review.

objectivesThe primary aim was to identify the number of patients requiring vasopressors beyond the first week of cervical spinal cord injury (SCI). Secondary objectives were to note the type, duration and doses of vasopressors and any association between prolonged vasopressors use and outcome.

settingNeurosurgical intensive care of a tertiary trauma care centre.

methodsAfter Ethical approval we retrospectively collected the data of patients of isolated cervical SCI admitted to neurosurgical intensive care from January to December 2017. Vasopressor requirement for sepsis or cardiac arrest was excluded.

resultsOut of 80 patients analysed, 54 (67.5%) received vasopressors. The prolonged requirement of vasopressors was observed in 77.7%. Our preferred agent was dopamine (64.8%). We found out that longer requirement (in days) of high dose of dopamine was associated with higher survival (p = 0.03).

conclusionOur results describe a significant portion of cervical SCI patients need ongoing vasopressor to maintain a mean arterial pressure >65 mm of Hg beyond first week. We observed patients who required longer duration of high dose dopamine had a higher chance of survival suggesting some unknown mechanism of high dose of dopamine. This is first such observation, further studies are needed to substantiate.

Indexed as

Cervical CordSpinal Cord InjuriesHumansRetrospective StudiesVasoconstrictor AgentsVasoconstrictor Agents

Identifiers

PMID34728603
PMCPMC8563917
OpenAlexW3208714975

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.